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7MIP

Mouse CTPS1 bound to inhibitor R80

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(C, D, G, I)
CTP synthase 1polymer59166770.44UniProt (P70698)
Pfam (PF06418)
Pfam (PF00117)
Mus musculus (Mouse)CTP synthetase 1,UTP--ammonia ligase 1
2E, I, M, Q
(C, D, G, I)
GLUTAMINEnon-polymer146.14Chemie (GLN)
3F, K, N, S
(C, D, G, I)
MAGNESIUM IONnon-polymer24.34Chemie (MG)
4G, L, O, T
(C, D, G, I)
URIDINE 5'-TRIPHOSPHATEnon-polymer484.14Chemie (UTP)
5H, J, P, R
(C, D, G, I)
N-(1-{2-[(cyclopropanesulfonyl)amino]-1,3-thiazol-4-yl}cyclopropyl)-5-(6-ethoxypyrazin-2-yl)pyridine-2-carboxamidenon-polymer486.64Chemie (ZG4)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight267081.6
Non-Polymers*Number of molecules16
Total formula weight4564.6
All*Total formula weight271646.2
*Water molecules are not included.

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PDB entries from 2026-01-14

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