7MII
Human CTPS2 bound to inhibitor T35
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, E | CTP synthase 2 | polymer | 586 | 65759.4 | 4 | UniProt (Q9NRF8) Pfam (PF06418) Pfam (PF00117) Pfam (PF07722) In PDB | Homo sapiens (Human) | CTP synthetase 2,UTP--ammonia ligase 2 |
2 | A, B, C, E | 2-{2-[(cyclopropanesulfonyl)amino]-1,3-thiazol-4-yl}-2-methyl-N-{5-[6-(trifluoromethyl)pyrazin-2-yl]pyridin-2-yl}propanamide | non-polymer | 512.5 | 4 | Chemie (ZFY) | |||
3 | A, B, C, E | URIDINE 5'-TRIPHOSPHATE | non-polymer | 484.1 | 4 | Chemie (UTP) | |||
4 | A, B, C, E | GLUTAMINE | non-polymer | 146.1 | 4 | Chemie (GLN) | |||
5 | A, B, C, E | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 263037.7 | |
Non-Polymers* | Number of molecules | 16 |
Total formula weight | 4668.5 | |
All* | Total formula weight | 267706.2 |