7MIH

Human CTPS2 bound to inhibitor R80

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, E)	CTP synthase 2	polymer	586	65759.4	4	UniProt (Q9NRF8) Pfam (PF06418) Pfam (PF00117) Pfam (PF07722)	Homo sapiens (Human)	CTP synthetase 2,UTP--ammonia ligase 2
2	E, J, M, R (A, B, C, E)	N-(1-{2-[(cyclopropanesulfonyl)amino]-1,3-thiazol-4-yl}cyclopropyl)-5-(6-ethoxypyrazin-2-yl)pyridine-2-carboxamide	non-polymer		486.6	4	Chemie (ZG4)
3	F, K, N, S (A, B, C, E)	URIDINE 5'-TRIPHOSPHATE	non-polymer		484.1	4	Chemie (UTP)
4	G, L, O, T (A, B, C, E)	GLUTAMINE	non-polymer		146.1	4	Chemie (GLN)
5	H, I, P, Q (A, B, C, E)	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	263037.7
Non-Polymers*	Number of molecules	16
	Total formula weight	4564.6
All*	Total formula weight	267602.3

*Water molecules are not included.