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7MIH

Human CTPS2 bound to inhibitor R80

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, ECTP synthase 2polymer58665759.44UniProt (Q9NRF8)
Pfam (PF06418)
Pfam (PF00117)
Pfam (PF07722)
In PDB
Homo sapiens (Human)CTP synthetase 2,UTP--ammonia ligase 2
2A, B, C, EN-(1-{2-[(cyclopropanesulfonyl)amino]-1,3-thiazol-4-yl}cyclopropyl)-5-(6-ethoxypyrazin-2-yl)pyridine-2-carboxamidenon-polymer486.64Chemie (ZG4)
3A, B, C, EURIDINE 5'-TRIPHOSPHATEnon-polymer484.14Chemie (UTP)
4A, B, C, EGLUTAMINEnon-polymer146.14Chemie (GLN)
5A, B, C, EMAGNESIUM IONnon-polymer24.34Chemie (MG)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight263037.7
Non-Polymers*Number of molecules16
Total formula weight4564.6
All*Total formula weight267602.3
*Water molecules are not included.

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PDB entries from 2024-07-10

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