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7MIG

Human CTPS1 bound to inhibitor T35

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(C, A, B, E)
CTP synthase 1polymer59166777.34UniProt (P17812)
Pfam (PF06418)
Pfam (PF00117)
Pfam (PF07722)
Homo sapiens (Human)CTP synthetase 1, UTP--ammonia ligase 1
2E, K, M, S
(C, A, B, E)
2-{2-[(cyclopropanesulfonyl)amino]-1,3-thiazol-4-yl}-2-methyl-N-{5-[6-(trifluoromethyl)pyrazin-2-yl]pyridin-2-yl}propanamidenon-polymer512.54Chemie (ZFY)
3F, L, N, T
(C, A, B, E)
GLUTAMINEnon-polymer146.14Chemie (GLN)
4G, I, O, Q
(C, A, B, E)
MAGNESIUM IONnon-polymer24.34Chemie (MG)
5H, J, P, R
(C, A, B, E)
URIDINE 5'-TRIPHOSPHATEnon-polymer484.14Chemie (UTP)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight267109.2
Non-Polymers*Number of molecules16
Total formula weight4668.5
All*Total formula weight271777.7
*Water molecules are not included.

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PDB entries from 2025-12-24

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