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7MIG

Human CTPS1 bound to inhibitor T35

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1C, A, B, ECTP synthase 1polymer59166777.34UniProt (P17812)
Pfam (PF06418)
Pfam (PF00117)
Pfam (PF07722)
In PDB
Homo sapiens (Human)CTP synthetase 1, UTP--ammonia ligase 1
2C, A, B, E2-{2-[(cyclopropanesulfonyl)amino]-1,3-thiazol-4-yl}-2-methyl-N-{5-[6-(trifluoromethyl)pyrazin-2-yl]pyridin-2-yl}propanamidenon-polymer512.54Chemie (ZFY)
3C, A, B, EGLUTAMINEnon-polymer146.14Chemie (GLN)
4C, A, B, EMAGNESIUM IONnon-polymer24.34Chemie (MG)
5C, A, B, EURIDINE 5'-TRIPHOSPHATEnon-polymer484.14Chemie (UTP)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight267109.2
Non-Polymers*Number of molecules16
Total formula weight4668.5
All*Total formula weight271777.7
*Water molecules are not included.

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PDB entries from 2024-07-24

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