7MIF
Human CTPS1 bound to inhibitor R80
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D (C, G, H, I) | CTP synthase 1 | polymer | 591 | 66777.3 | 4 | UniProt (P17812) Pfam (PF06418) Pfam (PF00117) Pfam (PF07722) | Homo sapiens (Human) | CTP synthetase 1, UTP--ammonia ligase 1 |
2 | E, K, M, S (C, G, H, I) | GLUTAMINE | non-polymer | 146.1 | 4 | Chemie (GLN) | |||
3 | F, L, O, T (C, G, H, I) | N-(1-{2-[(cyclopropanesulfonyl)amino]-1,3-thiazol-4-yl}cyclopropyl)-5-(6-ethoxypyrazin-2-yl)pyridine-2-carboxamide | non-polymer | 486.6 | 4 | Chemie (ZG4) | |||
4 | G, I, N, P (C, G, H) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
5 | H, J, Q, R (C, G, H, I) | URIDINE 5'-TRIPHOSPHATE | non-polymer | 484.1 | 4 | Chemie (UTP) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 267109.2 | |
Non-Polymers* | Number of molecules | 16 |
Total formula weight | 4564.6 | |
All* | Total formula weight | 271673.8 |