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7MGE

Structure of C9orf72:SMCR8:WDR41 in complex with ARF1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
WD repeat-containing protein 41polymer45951783.81UniProt (Q9HAD4)
Pfam (PF25178)
Homo sapiens (Human)
2B
(B)
Guanine nucleotide exchange protein SMCR8polymer937105149.11UniProt (Q8TEV9)
Pfam (PF11704)
Homo sapiens (Human)Smith-Magenis syndrome chromosomal region candidate gene 8 protein
3C
(C)
Guanine nucleotide exchange C9orf72polymer48154391.51UniProt (Q96LT7)
Pfam (PF15019)
Homo sapiens (Human)
4D
(E)
ADP-ribosylation factor 1polymer16618994.61UniProt (P84077)
Pfam (PF00025)
Homo sapiens (Human)
5E
(E)
GUANOSINE-5'-DIPHOSPHATEnon-polymer443.21Chemie (GDP)
6F
(E)
BERYLLIUM TRIFLUORIDE IONnon-polymer66.01Chemie (BEF)
7G
(E)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
Sequence modifications
E: 17 - 180 (UniProt: P84077)
PDBExternal DatabaseDetails
Ala 15-expression tag
Thr 16-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight230318.9
Non-Polymers*Number of molecules3
Total formula weight533.5
All*Total formula weight230852.5
*Water molecules are not included.

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PDB entries from 2026-01-28

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