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7MGE

Structure of C9orf72:SMCR8:WDR41 in complex with ARF1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
WD repeat-containing protein 41polymer45951783.81UniProt (Q9HAD4)
Pfam (PF25178)
Homo sapiens (Human)
2B
(B)
Guanine nucleotide exchange protein SMCR8polymer937105149.11UniProt (Q8TEV9)
Pfam (PF11704)
Homo sapiens (Human)Smith-Magenis syndrome chromosomal region candidate gene 8 protein
3C
(C)
Guanine nucleotide exchange C9orf72polymer48154391.51UniProt (Q96LT7)
Pfam (PF15019)
Homo sapiens (Human)
4D
(E)
ADP-ribosylation factor 1polymer16618994.61UniProt (P84077)
Pfam (PF00025)
Homo sapiens (Human)
5E
(E)
GUANOSINE-5'-DIPHOSPHATEnon-polymer443.21Chemie (GDP)
PubChem (136073927)
PubChem (135398619)
PubChem (135402030)
PubChem (135431654)
PubChem (135566337)
PubChem (135760556)
PubChem (136026707)
PubChem (136053418)
PubChem (136663964)
PubChem (136664748)
PubChem (136759848)
PubChem (136759849)
PubChem (136759850)
PubChem (136836636)
PubChem (136847074)
PubChem (172898537)
6F
(E)
BERYLLIUM TRIFLUORIDE IONnon-polymer66.01Chemie (BEF)
7G
(E)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
PubChem (888)
Sequence modifications
E: 17 - 180 (UniProt: P84077)
PDBExternal DatabaseDetails
Ala 15-expression tag
Thr 16-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight230318.9
Non-Polymers*Number of molecules3
Total formula weight533.5
All*Total formula weight230852.5
*Water molecules are not included.

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PDB entries from 2026-04-01

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