7MFF

Dimeric (BRAF)2:(14-3-3)2 complex bound to SB590885 Inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (C, D)	14-3-3 protein zeta/delta	polymer	245	27777.1	2	UniProt (P63104) Pfam (PF00244)	Homo sapiens (Human)	Protein kinase C inhibitor protein 1,KCIP-1
2	C, D (A, B)	Serine/threonine-protein kinase B-raf	polymer	766	84697.7	2	UniProt (P15056) Pfam (PF02196) Pfam (PF00130) Pfam (PF07714)	Homo sapiens (Human)	Proto-oncogene B-Raf,p94,v-Raf murine sarcoma viral oncogene homolog B1
3	E, F (A, B)	(1Z)-5-(2-{4-[2-(DIMETHYLAMINO)ETHOXY]PHENYL}-5-PYRIDIN-4-YL-1H-IMIDAZOL-4-YL)INDAN-1-ONE OXIME	non-polymer		453.5	2	Chemie (215)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	224949.6
Non-Polymers*	Number of molecules	2
	Total formula weight	907.1
All*	Total formula weight	225856.6

*Water molecules are not included.