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7MFF

Dimeric (BRAF)2:(14-3-3)2 complex bound to SB590885 Inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1C, D14-3-3 protein zeta/deltapolymer24527777.12UniProt (P63104)
Pfam (PF00244)
In PDB
Homo sapiens (Human)Protein kinase C inhibitor protein 1,KCIP-1
2A, BSerine/threonine-protein kinase B-rafpolymer76684697.72UniProt (P15056)
Pfam (PF02196)
Pfam (PF00130)
Pfam (PF07714)
In PDB
Homo sapiens (Human)Proto-oncogene B-Raf,p94,v-Raf murine sarcoma viral oncogene homolog B1
3A, B(1Z)-5-(2-{4-[2-(DIMETHYLAMINO)ETHOXY]PHENYL}-5-PYRIDIN-4-YL-1H-IMIDAZOL-4-YL)INDAN-1-ONE OXIMEnon-polymer453.52Chemie (215)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight224949.6
Non-Polymers*Number of molecules2
Total formula weight907.1
All*Total formula weight225856.6
*Water molecules are not included.

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PDB entries from 2024-08-14

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