7MEY
Structure of yeast Ubr1 in complex with Ubc2 and monoubiquitinated N-degron
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | E3 ubiquitin-protein ligase UBR1 | polymer | 1950 | 225102.8 | 1 | UniProt (P19812) Pfam (PF02207) Pfam (PF22960) Pfam (PF18995) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | N-end-recognizing protein,N-recognin-1,RING-type E3 ubiquitin transferase UBR1 |
| 2 | B (C) | Ubiquitin | polymer | 75 | 8493.7 | 1 | UniProt (P0CG47) Pfam (PF00240) | Homo sapiens (Human) | |
| 3 | C (B) | Ubiquitin-conjugating enzyme E2 2 | polymer | 172 | 19725.7 | 1 | UniProt (P06104) Pfam (PF00179) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | E2 ubiquitin-conjugating enzyme 2,Radiation sensitivity protein 6,Ubiquitin carrier protein UBC2,Ubiquitin-protein ligase UBC2 |
| 4 | D (D) | Ubiquitin | polymer | 75 | 8519.8 | 1 | UniProt (P0CG47) Pfam (PF00240) | Homo sapiens (Human) | |
| 5 | E (F) | Monoubiquitinated N-degron | polymer | 43 | 4571.2 | 1 | Saccharomyces cerevisiae S288C | ||
| 6 | F, G, H, I, J... (A) | ZINC ION | non-polymer | 65.4 | 7 | Chemie (ZN) | |||
| 7 | M (D) | 2-(ethylamino)ethane-1-thiol | non-polymer | 105.2 | 1 | Chemie (Z3V) |
Sequence modifications
C: 1 - 75 (UniProt: P0CG47)
| PDB | External Database | Details |
|---|---|---|
| Cys 48 | Lys 48 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 266413.2 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 563.1 | |
| All* | Total formula weight | 266976.2 |
