7MEX
Structure of yeast Ubr1 in complex with Ubc2 and N-degron
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (C) | Ubiquitin | polymer | 76 | 8622.9 | 1 | UniProt (P0CG48) Pfam (PF00240) | Homo sapiens | |
| 2 | B (B) | Ubiquitin-conjugating enzyme E2 2 | polymer | 150 | 17203.4 | 1 | UniProt (P06104) Pfam (PF00179) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | E2 ubiquitin-conjugating enzyme 2,Radiation sensitivity protein 6,Ubiquitin carrier protein UBC2,Ubiquitin-protein ligase UBC2 |
| 3 | C (D) | N-degron | polymer | 43 | 4571.2 | 1 | Saccharomyces cerevisiae S288C | ||
| 4 | D (A) | E3 ubiquitin-protein ligase UBR1 | polymer | 1950 | 225102.8 | 1 | UniProt (P19812) Pfam (PF02207) Pfam (PF22960) Pfam (PF18995) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | N-end-recognizing protein,N-recognin-1,RING-type E3 ubiquitin transferase UBR1 |
| 5 | E, F, G, H, I... (A) | ZINC ION | non-polymer | 65.4 | 7 | Chemie (ZN) |
Sequence modifications
C: 1 - 76 (UniProt: P0CG48)
| PDB | External Database | Details |
|---|---|---|
| Cys 76 | Gly 76 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 255500.3 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 457.9 | |
| All* | Total formula weight | 255958.1 |
