7MEW

E. coli MsbA in complex with G247

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	ATP-dependent lipid A-core flippase	polymer	605	67310.4	2	UniProt (A0A140NBS6) Pfam (PF00664) Pfam (PF00005) In PDB	Escherichia coli (strain B / BL21-DE3)	Lipid A export ATP-binding/permease protein MsbA
2	A, B	(2E)-3-{1-cyclopropyl-7-[(1S)-1-(3,6-dichloro-2-fluorophenyl)ethoxy]naphthalen-2-yl}prop-2-enoic acid	non-polymer		445.3	2	Chemie (Z5Y)

Sequence modifications

A, B: 1 - 582 (UniProt: A0A140NBS6)

PDB	External Database	Details
Met -22	-	initiating methionine
Gly -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
Ser -10	-	expression tag
Ser -9	-	expression tag
Gly -8	-	expression tag
His -7	-	expression tag
Ile -6	-	expression tag
Asp -5	-	expression tag
Asp -4	-	expression tag
Asp -3	-	expression tag
Asp -2	-	expression tag
Lys -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	134620.9
Non-Polymers*	Number of molecules	2
	Total formula weight	890.6
All*	Total formula weight	135511.5

*Water molecules are not included.