7MES
Structure of ALDH4A1 complexed with trans-4-Hydroxy-D-proline
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial | polymer | 563 | 61954.2 | 2 | UniProt (Q8CHT0) Pfam (PF00171) In PDB | Mus musculus (Mouse) | P5C dehydrogenase,Aldehyde dehydrogenase family 4 member A1,L-glutamate gamma-semialdehyde dehydrogenase |
2 | A, B | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 2 | Chemie (NAD) | |||
3 | A, B | (4S)-4-hydroxy-D-proline | non-polymer | 131.1 | 4 | Chemie (UY7) | |||
4 | A | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
5 | A, B | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 3 | Chemie (PEG) | |||
6 | A, B | PENTAETHYLENE GLYCOL | non-polymer | 238.3 | 2 | Chemie (1PE) | |||
7 | B | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
8 | water | water | 18.0 | 637 | Chemie (HOH) |
Sequence modifications
A, B: 22 - 563 (UniProt: Q8CHT0)
PDB | External Database | Details |
---|---|---|
Met 1 | - | expression tag |
Gly 2 | - | expression tag |
Ser 3 | - | expression tag |
Ser 4 | - | expression tag |
His 5 | - | expression tag |
His 6 | - | expression tag |
His 7 | - | expression tag |
His 8 | - | expression tag |
His 9 | - | expression tag |
His 10 | - | expression tag |
Ser 11 | - | expression tag |
Ser 12 | - | expression tag |
Gly 13 | - | expression tag |
Leu 14 | - | expression tag |
Val 15 | - | expression tag |
Pro 16 | - | expression tag |
Arg 17 | - | expression tag |
Gly 18 | - | expression tag |
Ser 19 | - | expression tag |
His 20 | - | expression tag |
Met 21 | - | expression tag |
Ala 33 | Thr 32 | conflict |
Thr 61 | Met 60 | conflict |
Lys 468 | Gln 467 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 123908.4 | |
Non-Polymers* | Number of molecules | 13 |
Total formula weight | 2990.7 | |
All* | Total formula weight | 126899.1 |