7MDL
High-resolution crystal structure of human SepSecS-tRNASec complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | O-phosphoseryl-tRNA(Sec) selenium transferase | polymer | 521 | 57944.5 | 4 | UniProt (Q9HD40) Pfam (PF05889) In PDB | Homo sapiens (Human) | Liver-pancreas antigen,LP,SLA-p35,SLA/LP autoantigen,Selenocysteine synthase,Sec synthase,Selenocysteinyl-tRNA(Sec) synthase,Sep-tRNA:Sec-tRNA synthase,SepSecS,Soluble liver antigen,SLA,UGA suppressor tRNA-associated protein,tRNA(Ser/Sec)-associated antigenic protein |
2 | E | RNA (90-MER) | polymer | 90 | 28908.1 | 1 | Synthetic construct | ||
3 | A, B, C, D | (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE | non-polymer | 233.2 | 4 | Chemie (PLR) | |||
4 | A, B, C, D | CITRATE ANION | non-polymer | 189.1 | 4 | Chemie (FLC) | |||
5 | water | water | 18.0 | 1309 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 501 (UniProt: Q9HD40)
PDB | External Database | Details |
---|---|---|
Met -19 | - | initiating methionine |
Gly -18 | - | expression tag |
Ser -17 | - | expression tag |
Ser -16 | - | expression tag |
His -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
Ser -9 | - | expression tag |
Ser -8 | - | expression tag |
Gly -7 | - | expression tag |
Leu -6 | - | expression tag |
Val -5 | - | expression tag |
Pro -4 | - | expression tag |
Arg -3 | - | expression tag |
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
His 0 | - | expression tag |
Ala 491 | Val 491 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 5 |
Total formula weight | 260686.1 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 1689.0 | |
All* | Total formula weight | 262375.1 |