7MC5
Crystal structure of the SARS-CoV-2 ExoN-nsp10 complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Proofreading exoribonuclease | polymer | 287 | 32421.4 | 1 | UniProt (P0DTD1) Pfam (PF06471) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | ExoN,Guanine-N7 methyltransferase,Non-structural protein 14,nsp14 |
| 2 | B (M) | Non-structural protein 10 | polymer | 140 | 14934.1 | 1 | UniProt (P0DTD1) Pfam (PF09401) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | nsp10, Growth factor-like peptide, GFL |
| 3 | C, D, X, Y (A, M) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 4 | AA, BA, CA, DA, E... (M, A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 23 | Chemie (EDO) | |||
| 5 | P, Q (A) | L(+)-TARTARIC ACID | non-polymer | 150.1 | 2 | Chemie (TLA) | |||
| 6 | V (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 7 | GA, HA (A, M) | water | water | 18.0 | 508 | Chemie (HOH) |
Sequence modifications
A: 3 - 289 (UniProt: P0DTD1)
M: 1 - 139 (UniProt: P0DTD1)
| PDB | External Database | Details |
|---|---|---|
| Gln 191 | Glu 6116 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 47355.5 | |
| Non-Polymers* | Number of molecules | 30 |
| Total formula weight | 2024.8 | |
| All* | Total formula weight | 49380.4 |
