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7M7N

Human DNA Pol eta with 2'-FA-ended primer and dAMPNPP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ADNA polymerase etapolymer43548617.71UniProt (Q9Y253)
Pfam (PF00817)
Pfam (PF21704)
Pfam (PF11799)
In PDB
Homo sapiens (Human)RAD30 homolog A,Xeroderma pigmentosum variant type protein
2TDNA (5'-D(*CP*AP*TP*TP*TP*TP*GP*AP*CP*GP*CP*T)-3')polymer123628.41Homo sapiens
3PDNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*(AF5))-3')polymer82453.61Homo sapiens
4A2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosinenon-polymer490.22Chemie (DZ4)
5AMAGNESIUM IONnon-polymer24.32Chemie (MG)
6AGLYCEROLnon-polymer92.13Chemie (GOL)
7waterwater18.0523Chemie (HOH)
Sequence modifications
A: 1 - 432 (UniProt: Q9Y253)
PDBExternal DatabaseDetails
Gly -2-expression tag
Pro -1-expression tag
His 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight54699.7
Non-Polymers*Number of molecules7
Total formula weight1305.3
All*Total formula weight56005.0
*Water molecules are not included.

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PDB entries from 2024-06-12

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