7M7E

6-Deoxyerythronolide B synthase (DEBS) hybrid module (M3/1) in complex with antibody fragment 1B2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (B, A)	6-deoxyerythronolide-B synthase EryA2, modules 3 and 4,EryAI,6-deoxyerythronolide-B synthase EryA3, modules 5 and 6 chimera	polymer	1777	187835.4	2	UniProt (Q03132) UniProt (Q5UNP6) UniProt (Q03133) Pfam (PF08990) Pfam (PF00109) Pfam (PF02801) Pfam (PF16197) Pfam (PF00698) Pfam (PF08659) Pfam (PF00550) Pfam (PF00975) UniProt (by SIFTS) (Q03131)	Saccharopolyspora erythraea (Streptomyces erythraeus)	DEBS M3/1TE
2	C (C)	1B2 (heavy chain)	polymer	249	26447.6	1		Homo sapiens (Human)
3	D (D)	1B2 (light chain)	polymer	236	25715.8	1		Homo sapiens (Human)

Sequence modifications

B, A: 4 - 924 (UniProt: Q03132)

PDB	External Database	Details
Met 1	-	expression tag
Ala 2	-	expression tag
Ser 3	-	expression tag

B, A: 925 - 1483 (UniProt: Q5UNP6)
B, A: 1484 - 1760 (UniProt: Q03133)

PDB	External Database	Details
Ser 1761	-	expression tag
Ser 1762	-	expression tag
Val 1763	-	expression tag
Asp 1764	-	expression tag
Lys 1765	-	expression tag
Leu 1766	-	expression tag
Ala 1767	-	expression tag
Ala 1768	-	expression tag
Ala 1769	-	expression tag
Leu 1770	-	expression tag
Glu 1771	-	expression tag
His 1772	-	expression tag
His 1773	-	expression tag
His 1774	-	expression tag
His 1775	-	expression tag
His 1776	-	expression tag
His 1777	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	427834.3
All*	Total formula weight	427834.3

*Water molecules are not included.