7M7E

6-Deoxyerythronolide B synthase (DEBS) hybrid module (M3/1) in complex with antibody fragment 1B2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (B, A)	6-deoxyerythronolide-B synthase EryA2, modules 3 and 4,EryAI,6-deoxyerythronolide-B synthase EryA3, modules 5 and 6 chimera	polymer	1777	187835.4	2	UniProt (Q03132) UniProt (Q5UNP6) UniProt (Q03133) UniProt (by SIFTS) (Q03131)	Saccharopolyspora erythraea (Streptomyces erythraeus)	DEBS M3/1TE
2	C (C)	1B2 (heavy chain)	polymer	249	26447.6	1		Homo sapiens (Human)
3	D (D)	1B2 (light chain)	polymer	236	25715.8	1		Homo sapiens (Human)

Sequence modifications

B, A: 4 - 924 (UniProt: Q03132)

PDB	External Database	Details
Met 1	-	expression tag
Ala 2	-	expression tag
Ser 3	-	expression tag

B, A: 925 - 1483 (UniProt: Q5UNP6)
B, A: 1484 - 1760 (UniProt: Q03133)

PDB	External Database	Details
Ser 1761	-	expression tag
Ser 1762	-	expression tag
Val 1763	-	expression tag
Asp 1764	-	expression tag
Lys 1765	-	expression tag
Leu 1766	-	expression tag
Ala 1767	-	expression tag
Ala 1768	-	expression tag
Ala 1769	-	expression tag
Leu 1770	-	expression tag
Glu 1771	-	expression tag
His 1772	-	expression tag
His 1773	-	expression tag
His 1774	-	expression tag
His 1775	-	expression tag
His 1776	-	expression tag
His 1777	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	427834.3
All*	Total formula weight	427834.3

*Water molecules are not included.