7M4T
Menin bound to M-1121
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Menin | polymer | 550 | 61061.2 | 1 | UniProt (O00255) Pfam (PF05053) | Homo sapiens (Human) | |
| 2 | B (A) | methyl {(1S,2R)-2-[(1S)-2-(azetidin-1-yl)-1-(3-fluorophenyl)-1-{1-[(3-methoxy-1-{4-[(1S,4S)-5-propanoyl-2,5-diazabicyclo[2.2.1]heptane-2-sulfonyl]phenyl}azetidin-3-yl)methyl]piperidin-4-yl}ethyl]cyclopentyl}carbamate | non-polymer | 795.0 | 1 | Chemie (YQV) | |||
| 3 | C, D, E, F, G (A) | praseodymium triacetate | non-polymer | 318.0 | 5 | Chemie (7PR) | |||
| 4 | H (A) | water | water | 18.0 | 1 | Chemie (HOH) |
Sequence modifications
A: 2 - 459 (UniProt: O00255)
A: 520 - 610 (UniProt: O00255)
| PDB | External Database | Details |
|---|---|---|
| Ser 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 61061.2 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2385.2 | |
| All* | Total formula weight | 63446.5 |
