7M32
Dihydropyrimidine Dehydrogenase (DPD) C671A Mutant Soaked with Uracil and NADPH Anaerobically
エンティティ
| Entity ID | 鎖名 | 説明 | 種類 | 鎖長 | 化学式量 | 分子数 | データベース名(アクセス番号) | 由来する生物種 | エンティティの一般名 |
| 1 | A, B, C, D (A, B, C, D) | Dihydropyrimidine dehydrogenase [NADP(+)] | polymer | 1025 | 111571.3 | 4 | UniProt (Q28943) Pfam (PF14691) Pfam (PF07992) Pfam (PF01180) Pfam (PF14697) | Sus scrofa (Pig) | DHPDHase,DPD,Dihydrothymine dehydrogenase,Dihydrouracil dehydrogenase |
| 2 | E, EA, F, FA, G... (A, D, B, C) | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 16 | Chemie (SF4) | |||
| 3 | I, IA, R, Z (A, D, B, C) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 4 | Chemie (FAD) | |||
| 4 | AA, J, JA, S (C, A, D, B) | URACIL | non-polymer | 112.1 | 4 | Chemie (URA) | |||
| 5 | BA, K, KA, T (C, A, D, B) | 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL | non-polymer | 458.4 | 4 | Chemie (FNR) | |||
| 6 | DA, L (D, A) | ALANINE | non-polymer | 89.1 | 2 | Chemie (ALA) | |||
| 7 | CA, M (D, B) | LEUCINE | non-polymer | 131.2 | 2 | Chemie (LEU) | |||
| 8 | U (C) | PROLINE | non-polymer | 115.1 | 1 | Chemie (PRO) | |||
| 9 | LA, MA, NA, OA (A, B, C, D) | water | water | 18.0 | 2630 | Chemie (HOH) |
配列変更
A, B, C, D: 1 - 1025 (UniProt: Q28943)
| PDB | 外部データベース | 詳細 |
|---|---|---|
| Asp 60 | Gly 60 | conflict |
| Ala 671 | Cys 671 | engineered mutation |
配列ビューア
非対称単位の内容
| タンパク質・ 核酸鎖 | 鎖の数 | 4 |
| 化学式量合計 | 446285.1 | |
| タンパク質・ 核酸・ 糖鎖以外* | 分子数 | 33 |
| 化学式量合計 | 11605.9 | |
| 全て* | 化学式量合計 | 457891.0 |
