7M2I
Structural Snapshots of Intermediates in the Gating of a K+ Channel
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Monoclonal antibody (IgG) against KcsA, Fab heavy chain | polymer | 219 | 23411.2 | 1 | Mus musculus (Mouse) | ||
| 2 | B (B) | Monoclonal antibody (IgG) against KcsA, Fab light chain | polymer | 212 | 23435.7 | 1 | Mus musculus (Mouse) | ||
| 3 | C (C) | pH-gated potassium channel KcsA | polymer | 96 | 10134.8 | 1 | UniProt (P0A334) Pfam (PF00520) Pfam (PF07885) | Streptomyces lividans | Streptomyces lividans K+ channel,SKC1 |
| 4 | D (A) | NONAN-1-OL | non-polymer | 144.3 | 1 | Chemie (F09) | |||
| 5 | E (C) | (1S)-2-HYDROXY-1-[(NONANOYLOXY)METHYL]ETHYL MYRISTATE | non-polymer | 442.7 | 1 | Chemie (1EM) | |||
| 6 | F, G, H, I, J... (C) | POTASSIUM ION | non-polymer | 39.1 | 6 | Chemie (K) | |||
| 7 | L, M, N (A, B, C) | water | water | 18.0 | 24 | Chemie (HOH) |
Sequence modifications
C: 26 - 116 (UniProt: P0A334)
| PDB | External Database | Details |
|---|---|---|
| Cys 28 | Ala 28 | conflict |
| Phe 67 | Trp 67 | conflict |
| Gln 117 | - | expression tag |
| Cys 118 | - | expression tag |
| Gln 119 | - | expression tag |
| Gln 120 | - | expression tag |
| Gln 121 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 56981.8 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 821.5 | |
| All* | Total formula weight | 57803.3 |
