7M2E
Crystal structure of BPTF bromodomain in complex with CB02-092
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Nucleosome-remodeling factor subunit BPTF | polymer | 123 | 14455.4 | 1 | UniProt (Q12830) Pfam (PF00439) In PDB | Homo sapiens (Human) | Bromodomain and PHD finger-containing transcription factor,Fetal Alz-50 clone 1 protein,Fetal Alzheimer antigen |
| 2 | A | 4-chloro-5-{4-[2-(dimethylamino)ethyl]anilino}-2-methylpyridazin-3(2H)-one | non-polymer | 306.8 | 1 | Chemie (YOV) | |||
| 3 | water | water | 18.0 | 164 | Chemie (HOH) |
Sequence modifications
A: 2917 - 3037 (UniProt: Q12830)
| PDB | External Database | Details |
|---|---|---|
| Ser 2915 | - | expression tag |
| Met 2916 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 14455.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 306.8 | |
| All* | Total formula weight | 14762.2 |
