7M1X

Cryo-EM Structure of Nucleosome containing mouse histone variant H2A.Z

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (I)	DNA (136-MER)	polymer	147	45604.0	1		unidentified
2	B (J)	DNA (136-MER)	polymer	147	45145.8	1		unidentified
3	C, G (A, E)	Histone H3	polymer	136	15507.2	2	UniProt (A0A310TTQ1) Pfam (PF00125) UniProt (by SIFTS) (P02302)	Xenopus laevis (African clawed frog)
4	D, H (B, F)	Histone H4	polymer	103	11394.4	2	UniProt (P62799) Pfam (PF15511)	Xenopus laevis (African clawed frog)
5	E, I (C, G)	Histone H2A.Z	polymer	128	13581.8	2	UniProt (P0C0S6) Pfam (PF00125) Pfam (PF16211)	Mus musculus (Mouse)	H2A/z
6	F, J (D, H)	Histone H2B 1.1	polymer	126	13979.3	2	UniProt (P02281) Pfam (PF00125)	Xenopus laevis (African clawed frog)	H2B1.1

Sequence modifications

A, E: 400 - 535 (UniProt: A0A310TTQ1)

PDB	External Database	Details
Glu 434	Gly 35	conflict

D, H: 1197 - 1322 (UniProt: P02281)

PDB	External Database	Details
Thr 1229	Ser 33	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	199675.2
All*	Total formula weight	199675.2

*Water molecules are not included.