7M18

HeLa-tubulin in complex with cryptophycin 1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	B, D, F, H, J...	Tubulin beta-3 chain	polymer	450	50481.5	8	UniProt (Q13509) Pfam (PF00091) Pfam (PF03953) In PDB	Homo sapiens (Human)	Tubulin beta-4 chain,Tubulin beta-III
2	A, C, E, G, I...	Tubulin alpha-1B chain	polymer	451	50204.4	8	UniProt (P68363) Pfam (PF00091) Pfam (PF03953) In PDB	Homo sapiens (Human)	Alpha-tubulin ubiquitous,Tubulin K-alpha-1,Tubulin alpha-ubiquitous chain
3	J, L, N, P, B...	Cryptophycin 1	non-polymer		655.2	8	Chemie (YNP)
4	H, J, L, N, P...	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	8	Chemie (GDP)
5	G, I, K, M, O...	GUANOSINE-5'-TRIPHOSPHATE	non-polymer		523.2	8	Chemie (GTP)

Contents of the asymmetric unit

Polymers	Number of chains	16
	Total formula weight	805487.7
Non-Polymers*	Number of molecules	24
	Total formula weight	12972.5
All*	Total formula weight	818460.2

*Water molecules are not included.