7M0I

Crystal structure of a human metapneumovirus subtype B2 trimeric fusion protein

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G, I... (G, I, K, A, C...)	Fusion glycoprotein F2	polymer	89	10195.5	6	UniProt (C6F474)	Human metapneumovirus
2	B, D, F, H, J... (H, J, L, B, D...)	Fusion glycoprotein F1	polymer	431	46813.9	6	UniProt (C6F474) Pfam (PF00523)	Human metapneumovirus
3	AA, BA, CA, DA, M... (D, E, F, G, H...)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	18	Chemie (NAG)
4	EA, FA, GA, HA, IA... (H, I, J, L, B...)	water	water		18.0	25	Chemie (HOH)

Sequence modifications

G, I, K, A, C, E: 23 - 101 (UniProt: C6F474)

PDB	External Database	Details
Leu 19	-	expression tag
Lys 20	-	expression tag
Glu 21	-	expression tag
Ser 22	-	expression tag
Lys 102	-	expression tag
Lys 103	-	expression tag
Arg 104	-	expression tag
Lys 105	-	expression tag
Arg 106	-	expression tag
Arg 107	-	expression tag

H, J, L, B, D, F: 112 - 489 (UniProt: C6F474)

PDB	External Database	Details
Ser 490	-	expression tag
Gly 491	-	expression tag
Arg 492	-	expression tag
Glu 493	-	expression tag
Asn 494	-	expression tag
Leu 495	-	expression tag
Tyr 496	-	expression tag
Phe 497	-	expression tag
Gln 498	-	expression tag
Gly 499	-	expression tag
Gly 500	-	expression tag
Gly 501	-	expression tag
Gly 502	-	expression tag
Gly 503	-	expression tag
Ser 504	-	expression tag
Gly 505	-	expression tag
Tyr 506	-	expression tag
Ile 507	-	expression tag
Pro 508	-	expression tag
Glu 509	-	expression tag
Ala 510	-	expression tag
Pro 511	-	expression tag
Arg 512	-	expression tag
Asp 513	-	expression tag
Gln 514	-	expression tag
Ala 515	-	expression tag
Tyr 516	-	expression tag
Val 517	-	expression tag
Arg 518	-	expression tag
Lys 519	-	expression tag
Asp 520	-	expression tag
Gly 521	-	expression tag
Glu 522	-	expression tag
Trp 523	-	expression tag
Val 524	-	expression tag
Leu 525	-	expression tag
Leu 526	-	expression tag
Ser 527	-	expression tag
Thr 528	-	expression tag
Phe 529	-	expression tag
Leu 530	-	expression tag
Gly 531	-	expression tag
Gly 532	-	expression tag
Thr 533	-	expression tag
Glu 534	-	expression tag
Gly 535	-	expression tag
Arg 536	-	expression tag
His 537	-	expression tag
His 538	-	expression tag
His 539	-	expression tag
His 540	-	expression tag
His 541	-	expression tag
His 542	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	342056.3
Non-Polymers*	Number of molecules	18
	Total formula weight	3981.7
All*	Total formula weight	346038.0

*Water molecules are not included.