7M06

Dihydrodipicolinate synthase (DHDPS) from C.jejuni, Y110F mutant with R,R-bislysine bound at the allosteric site at 2.7 Angstrom

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	4-hydroxy-tetrahydrodipicolinate synthase	polymer	310	34100.2	4	UniProt (Q9PPB4) Pfam (PF00701)	Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)	HTPA synthase
2	E, F, I, M, N... (A, B, C, D)	MAGNESIUM ION	non-polymer		24.3	9	Chemie (MG)
3	G, J, Q, T (A, B, C, D)	TRIETHYLENE GLYCOL	non-polymer		150.2	4	Chemie (PGE)
4	H, L (B, C)	(2R,5R)-2,5-diamino-2,5-bis(4-aminobutyl)hexanedioic acid	non-polymer		318.4	2	Chemie (3VN)
5	K, U (B, D)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	2	Chemie (PEG)
6	V (D)	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
7	W, X, Y, Z (A, B, C, D)	water	water		18.0	92	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 298 (UniProt: Q9PPB4)

PDB	External Database	Details
Met -11	-	expression tag
Arg -10	-	expression tag
Gly -9	-	expression tag
Ser -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
Phe 110	Tyr 110	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	136400.9
Non-Polymers*	Number of molecules	18
	Total formula weight	1730.6
All*	Total formula weight	138131.4

*Water molecules are not included.