7LYE
Myotoxin I from Bothrops moojeni co-crystallized with synthetic inhibitor Varespladib (LY315920)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Basic phospholipase A2 homolog BomoTx | polymer | 122 | 13839.2 | 4 | UniProt (A0A1S5XW05) UniProt (by SIFTS) (P82114) | Bothrops moojeni (Lance-headed viper Caissaca) | svPLA2 homolog |
| 2 | E, F, H, I (A, B, C, D) | ({3-[amino(oxo)acetyl]-1-benzyl-2-ethyl-1H-indol-4-yl}oxy)acetic acid | non-polymer | 380.4 | 4 | Chemie (VRD) | |||
| 3 | G (B) | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL | non-polymer | 354.4 | 1 | Chemie (PE4) | |||
| 4 | J, K, L, M (A, B, C, D) | water | water | 18.0 | 447 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 122 (UniProt: A0A1S5XW05)
| PDB | External Database | Details |
|---|---|---|
| Asn 70 | Asp 86 | conflict |
| Ala 80 | Ser 96 | conflict |
| Asp 117 | Lys 133 | conflict |
| Leu 120 | Asp 136 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 55356.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1876.0 | |
| All* | Total formula weight | 57232.6 |
