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7LW1

Human phosphofructokinase-1 liver type bound to activator NA-11

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, D, E, F)
ATP-dependent 6-phosphofructokinase, liver typepolymer78085120.44UniProt (P17858)
Pfam (PF00365)
Homo sapiens (Human)ATP-PFK,PFK-L,6-phosphofructokinase type B,Phosphofructo-1-kinase isozyme B,PFK-B,Phosphohexokinase
2E, I, M, Q
(A, D, E, F)
N-{(11S)-2-[2-(5-hydroxypent-1-yn-1-yl)phenyl]-4H,10H-pyrazolo[5,1-c][1,4]benzoxazepin-7-yl}acetamidenon-polymer401.54Chemie (YG1)
3F, J, N, R
(A, D, E, F)
1,6-di-O-phosphono-beta-D-fructofuranosenon-polymer340.14Chemie (FBP)
4G, K, O, S
(A, D, E, F)
6-O-phosphono-beta-D-fructofuranosenon-polymer260.14Chemie (F6P)
5H, L, P, T
(A, D, E, F)
ADENOSINE-5'-DIPHOSPHATEnon-polymer427.24Chemie (ADP)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight340481.5
Non-Polymers*Number of molecules16
Total formula weight5715.6
All*Total formula weight346197.1
*Water molecules are not included.

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PDB entries from 2025-12-17

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