7LVJ
CASP8 isoform G DED domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Isoform 9 of Caspase-8 | polymer | 257 | 30014.5 | 1 | UniProt (Q14790-9) Pfam (PF01335) UniProt (by SIFTS) (Q14790) | Homo sapiens (Human) | CASP-8,Apoptotic cysteine protease,Apoptotic protease Mch-5,CAP4,FADD-homologous ICE/ced-3-like protease,FADD-like ICE,FLICE,ICE-like apoptotic protease 5,MORT1-associated ced-3 homolog,MACH |
| 2 | B (A) | water | water | 18.0 | 187 | Chemie (HOH) |
Sequence modifications
A: 2 - 247 (UniProt: Q14790-9)
| PDB | External Database | Details |
|---|---|---|
| Met -1 | - | initiating methionine |
| Ser 0 | - | expression tag |
| Leu 1 | - | expression tag |
| Ala 181 | Phe 181 | conflict |
| Asp 187 | Ile 187 | conflict |
| Glu 248 | - | expression tag |
| Gly 249 | - | expression tag |
| His 250 | - | expression tag |
| His 251 | - | expression tag |
| His 252 | - | expression tag |
| His 253 | - | expression tag |
| His 254 | - | expression tag |
| His 255 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 30014.5 | |
| All* | Total formula weight | 30014.5 |
