7LUN
Human PARP14 (ARTD8), catalytic fragment in complex with RBN011980
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Protein mono-ADP-ribosyltransferase PARP14 | polymer | 194 | 22172.6 | 8 | UniProt (Q460N5) Pfam (PF00644) | Homo sapiens (Human) | ADP-ribosyltransferase diphtheria toxin-like 8,ARTD8,B aggressive lymphoma protein 2,Poly [ADP-ribose] polymerase 14,PARP-14 |
| 2 | I, J, K, L, M... (A, B, C, D, E...) | 7-(cyclopentylamino)-5-fluoro-2-{[(trans-4-hydroxycyclohexyl)sulfanyl]methyl}quinazolin-4(3H)-one | non-polymer | 391.5 | 8 | Chemie (YFG) | |||
| 3 | N (E) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | P, S (F, H) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | AA, T, U, V, W... (H, A, B, C, D...) | water | water | 18.0 | 405 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 1611 - 1801 (UniProt: Q460N5)
| PDB | External Database | Details |
|---|---|---|
| Ser 1608 | - | expression tag |
| Asn 1609 | - | expression tag |
| Ala 1610 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 177380.6 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 3351.7 | |
| All* | Total formula weight | 180732.3 |
