7LUF

HSV1 polymerase ternary complex with dsDNA and PNU-183792

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	DNA polymerase	polymer	1163	129637.0	2	UniProt (I7GY94) Pfam (PF03104) Pfam (PF00136) UniProt (by SIFTS) (P04293) In PDB	Human herpesvirus 1 (HHV-1 Human herpes simplex virus 1)
2	C, E	DNA (5'-D(P*AP*TP*GP*GP*TP*AP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*CP*G)-3')	polymer	27	8461.5	2		synthetic construct
3	D, F	DNA (5'-D(*CP*GP*AP*TP*CP*CP*TP*TP*CP*CP*CP*CP*TP*AP*C)-3')	polymer	23	6921.5	2		synthetic construct
4	C, E	N-(4-chlorobenzyl)-1-methyl-6-(morpholinomethyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide	non-polymer		425.9	2	Chemie (YE4)

Sequence modifications

A, B: 43 - 1197 (UniProt: I7GY94)

PDB	External Database	Details
Leu 35	-	expression tag
Glu 36	-	expression tag
Val 37	-	expression tag
Leu 38	-	expression tag
Phe 39	-	expression tag
Gln 40	-	expression tag
Gly 41	-	expression tag
Pro 42	-	expression tag
Ala 370	Glu 370	conflict

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	290039.8
Non-Polymers*	Number of molecules	2
	Total formula weight	851.8
All*	Total formula weight	290891.6

*Water molecules are not included.