7LT3

NHEJ Long-range synaptic complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, J	X-ray repair cross-complementing protein 6	polymer	609	69945.0	2	UniProt (P12956) Pfam (PF03731) Pfam (PF02735) Pfam (PF03730) Pfam (PF02037) In PDB	Homo sapiens (Human)	5'-deoxyribose-5-phosphate lyase Ku70,5'-dRP lyase Ku70,70 kDa subunit of Ku antigen,ATP-dependent DNA helicase 2 subunit 1,ATP-dependent DNA helicase II 70 kDa subunit,CTC box-binding factor 75 kDa subunit,CTCBF,DNA repair protein XRCC6,Lupus Ku autoantigen protein p70,Ku70,Thyroid-lupus autoantigen,TLAA,X-ray repair complementing defective repair in Chinese hamster cells 6
2	B, K	X-ray repair cross-complementing protein 5	polymer	732	82812.4	2	UniProt (P13010) Pfam (PF03731) Pfam (PF02735) Pfam (PF03730) Pfam (PF08785) In PDB	Homo sapiens (Human)	86 kDa subunit of Ku antigen,ATP-dependent DNA helicase 2 subunit 2,ATP-dependent DNA helicase II 80 kDa subunit,CTC box-binding factor 85 kDa subunit,CTCBF,DNA repair protein XRCC5,Ku80,Ku86,Lupus Ku autoantigen protein p86,Nuclear factor IV,Thyroid-lupus autoantigen,TLAA,X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
3	C, L	DNA-dependent protein kinase catalytic subunit	polymer	4128	469673.2	2	UniProt (P78527) Pfam (PF08163) Pfam (PF19704) Pfam (PF02259) Pfam (PF00454) Pfam (PF02260) Pfam (PF20502) In PDB	Homo sapiens (Human)	DNA-PKcs,DNPK1,p460
4	Q, R	Unknown peptide	polymer	20	1720.1	2		Homo sapiens (Human)
5	D, M	DNA (31-MER)	polymer	31	9510.2	2		Homo sapiens
6	E, N	DNA (30-MER)	polymer	30	9237.0	2		Homo sapiens
7	F, G, O, P	DNA repair protein XRCC4	polymer	336	38337.7	4	UniProt (Q13426) Pfam (PF06632) Pfam (PF21924) Pfam (PF21925) In PDB	Homo sapiens (Human)	X-ray repair cross-complementing protein 4
8	H, I	Non-homologous end-joining factor 1	polymer	299	33372.2	2	UniProt (Q9H9Q4) Pfam (PF09302) Pfam (PF21928) In PDB	Homo sapiens (Human)	Protein cernunnos,XRCC4-like factor
9	X, Y	DNA ligase 4	polymer	911	104125.0	2	UniProt (P49917) Pfam (PF04675) Pfam (PF01068) Pfam (PF04679) Pfam (PF00533) Pfam (PF11411) In PDB	Homo sapiens (Human)	DNA ligase IV,Polydeoxyribonucleotide synthase [ATP] 4
10	C, L	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	2	Chemie (ADP)

Contents of the asymmetric unit

Polymers	Number of chains	20
	Total formula weight	1714141.1
Non-Polymers*	Number of molecules	2
	Total formula weight	854.4
All*	Total formula weight	1714995.5

*Water molecules are not included.