7LS0
Structure of the Human ALK GRD bound to AUG
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | ALK tyrosine kinase receptor fused with ALK and LTK ligand 2 | polymer | 451 | 47374.7 | 4 | UniProt (Q9UM73) UniProt (Q6UX46) Pfam (PF12810) Pfam (PF15129) In PDB | Homo sapiens (Human) | Anaplastic lymphoma kinase,Augmentor alpha,AUG-alpha,Protein FAM150B |
2 | A | CITRIC ACID | non-polymer | 192.1 | 2 | Chemie (CIT) | |||
3 | D | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) |
Sequence modifications
A, B, C, D: 678 - 1030 (UniProt: Q9UM73)
A, B, C, D: 1046 - 1113 (UniProt: Q6UX46)
PDB | External Database | Details |
---|---|---|
Gly 663 | - | expression tag |
His 664 | - | expression tag |
His 665 | - | expression tag |
His 666 | - | expression tag |
His 667 | - | expression tag |
His 668 | - | expression tag |
His 669 | - | expression tag |
His 670 | - | expression tag |
His 671 | - | expression tag |
Ile 672 | - | expression tag |
Glu 673 | - | expression tag |
Gly 674 | - | expression tag |
Arg 675 | - | expression tag |
Ser 676 | - | expression tag |
Leu 677 | - | expression tag |
Gly 1031 | - | linker |
Gly 1032 | - | linker |
Ser 1033 | - | linker |
Gly 1034 | - | linker |
Gly 1035 | - | linker |
Ser 1036 | - | linker |
Gly 1037 | - | linker |
Gly 1038 | - | linker |
Ser 1039 | - | linker |
Gly 1040 | - | linker |
Gly 1041 | - | linker |
Ser 1042 | - | linker |
Gly 1043 | - | linker |
Gly 1044 | - | linker |
Ala 1045 | - | linker |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 189498.8 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 605.5 | |
All* | Total formula weight | 190104.3 |