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7LRQ

Crystal structure of human SFPQ/NONO heterodimer, conserved DBHS region

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Splicing factor, proline- and glutamine-richpolymer26029834.71UniProt (P23246)
Pfam (PF00076)
Pfam (PF08075)
Homo sapiens (Human)100 kDa DNA-pairing protein,hPOMp100,DNA-binding p52/p100 complex,100 kDa subunit,Polypyrimidine tract-binding protein-associated-splicing factor,PSF,PTB-associated-splicing factor
2B
(B)
Non-POU domain-containing octamer-binding proteinpolymer26030147.51UniProt (Q15233)
Pfam (PF00076)
Pfam (PF08075)
Homo sapiens (Human)NonO protein,54 kDa nuclear RNA- and DNA-binding protein,55 kDa nuclear protein,DNA-binding p52/p100 complex,52 kDa subunit,NMT55,p54(nrb),p54nrb
3C, D, E, F, G
(A, B)
CHLORIDE IONnon-polymer35.55Chemie (CL)
4H, I
(A, B)
waterwater18.057Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight59982.2
Non-Polymers*Number of molecules5
Total formula weight177.3
All*Total formula weight60159.5
*Water molecules are not included.

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PDB entries from 2025-12-17

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