7LRF

Netrin-1 in complex with SOS

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Netrin-1	polymer	443	49579.9	2	UniProt (Q90922) Pfam (PF00055) Pfam (PF00053) In PDB	Gallus gallus (Chicken)
2	C	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	1	In PDB GlyTouCan (G15407YE)
3	D, E, F, G, H...	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	7	In PDB GlyTouCan (G42666HT)
4	K, L	1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose	branched		982.8	2	In PDB BIRD (PRD_900013)
5	A, B	1,2-ETHANEDIOL	non-polymer		62.1	4	Chemie (EDO)
6	A, B	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	2	Chemie (PEG)
7	A, B	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
8	A	SODIUM ION	non-polymer		23.0	1	Chemie (NA)
9	B	2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID	non-polymer		207.3	1	Chemie (NHE)
10	B	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
11		water	water		18.0	42	Chemie (HOH)

Sequence modifications

A, B: 26 - 458 (UniProt: Q90922)

PDB	External Database	Details
Ala 22	-	expression tag
Pro 23	-	expression tag
Leu 24	-	expression tag
Ala 25	-	expression tag
Gly 459	-	expression tag
Ser 460	-	expression tag
Leu 461	-	expression tag
Val 462	-	expression tag
Pro 463	-	expression tag
Arg 464	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	99159.9
Branched	Number of molecules	10
	Total formula weight	5523.0
Non-Polymers*	Number of molecules	11
	Total formula weight	806.4
All*	Total formula weight	105489.2

*Water molecules are not included.