7LPY
Crystal structures and ribonuclease activity of the Flavivirus host factor ERI3 that is involved in viral RNA synthesis define the ERI subfamily of structure-specific 3-prime - 5-prime exoribonucleases
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | ERI1 exoribonuclease 3 | polymer | 216 | 25068.1 | 2 | UniProt (O43414) Pfam (PF00929) In PDB | Homo sapiens (Human) | Prion interactor 1,Prion protein-interacting protein |
2 | A, B | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 2 | Chemie (AMP) | |||
3 | A, B | MANGANESE (II) ION | non-polymer | 54.9 | 4 | Chemie (MN) | |||
4 | B | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
5 | water | water | 18.0 | 158 | Chemie (HOH) |
Sequence modifications
A, B: 137 - 337 (UniProt: O43414)
PDB | External Database | Details |
---|---|---|
Met 122 | - | initiating methionine |
His 123 | - | expression tag |
His 124 | - | expression tag |
His 125 | - | expression tag |
His 126 | - | expression tag |
His 127 | - | expression tag |
His 128 | - | expression tag |
Glu 129 | - | expression tag |
Asn 130 | - | expression tag |
Leu 131 | - | expression tag |
Tyr 132 | - | expression tag |
Phe 133 | - | expression tag |
Gln 134 | - | expression tag |
Ser 135 | - | expression tag |
Met 136 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 50136.1 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 1006.3 | |
All* | Total formula weight | 51142.4 |