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7LON

Ornithine Aminotransferase (OAT) cocrystallized with its inactivator - (1S,3S)-3-amino-4-(difluoromethylene)cyclohexene-1-carboxylic acid

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(B, A, C)
Ornithine aminotransferase, mitochondrialpolymer40444860.33UniProt (P04181)
Pfam (PF00202)
Homo sapiens (Human)Ornithine delta-aminotransferase,Ornithine--oxo-acid aminotransferase
2D, F, H
(B, A, C)
THREONINEnon-polymer119.13Chemie (THR)
3E, G, I
(B, A, C)
(1R,3S,4R)-3-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]-4-methylcyclohexane-1-carboxylic acidnon-polymer388.43Chemie (7QP)
4J, K, L
(B, A, C)
waterwater18.0574Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight134581.0
Non-Polymers*Number of molecules6
Total formula weight1522.4
All*Total formula weight136103.4
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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