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7LNH

S-adenosylmethionine synthetase co-crystallized with UppNHp

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
S-adenosylmethionine synthase isoform type-2polymer39543720.62UniProt (P31153)
Pfam (PF00438)
Pfam (PF02772)
Pfam (PF02773)
Homo sapiens (Human)AdoMet synthase 2,Methionine adenosyltransferase 2,MAT 2,Methionine adenosyltransferase II,MAT-II
2C, E
(A, B)
(2~{S})-2-azanyl-4-[[(2~{S},3~{S},4~{R},5~{R})-5-[2,4-bis(oxidanylidene)pyrimidin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl-methyl-$l^{3}-sulfanyl]butanoic acidnon-polymer375.42Chemie (YQP)
3D
(B)
1,2-ETHANEDIOLnon-polymer62.11Chemie (EDO)
4F, G
(A, B)
waterwater18.028Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight87441.3
Non-Polymers*Number of molecules3
Total formula weight812.9
All*Total formula weight88254.1
*Water molecules are not included.

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PDB entries from 2025-12-03

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