7LKY
Crystal Structure of PHF1 Tudor domain in complex with a peptidomimetic ligand UNC6641
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Isoform 1 of PHD finger protein 1 | polymer | 64 | 7206.2 | 8 | UniProt (O43189) Pfam (PF18104) | Homo sapiens (Human) | hPHF1,Polycomb-like protein 1,hPCl1 |
| 2 | I, J, K, L, M... (J, I, K, L, M...) | Peptidomimetic inhibitor UNC6641 | polymer | 8 | 1002.3 | 8 | synthetic construct | ||
| 3 | Q, R, S, U, W... (A, C, D, E, H) | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) | |||
| 4 | T, V, X (D, E, G) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 3 | Chemie (DMS) | |||
| 5 | AA, BA, CA, DA, EA... (B, C, D, E, F...) | water | water | 18.0 | 258 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 28 - 87 (UniProt: O43189)
| PDB | External Database | Details |
|---|---|---|
| Gly 24 | - | expression tag |
| Pro 25 | - | expression tag |
| Leu 26 | - | expression tag |
| Gly 27 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 16 |
| Total formula weight | 65667.8 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 626.9 | |
| All* | Total formula weight | 66294.6 |
