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7LKY

Crystal Structure of PHF1 Tudor domain in complex with a peptidomimetic ligand UNC6641

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E...Isoform 1 of PHD finger protein 1polymer647206.28UniProt (O43189)
Pfam (PF18104)
In PDB
Homo sapiens (Human)hPHF1,Polycomb-like protein 1,hPCl1
2J, I, K, L, M...Peptidomimetic inhibitor UNC6641polymer81002.38synthetic construct
3A, C, D, E, HZINC IONnon-polymer65.46Chemie (ZN)
4D, E, GDIMETHYL SULFOXIDEnon-polymer78.13Chemie (DMS)
5waterwater18.0258Chemie (HOH)
Sequence modifications
A, B, C, D, E, F, G, H: 28 - 87 (UniProt: O43189)
PDBExternal DatabaseDetails
Gly 24-expression tag
Pro 25-expression tag
Leu 26-expression tag
Gly 27-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains16
Total formula weight65667.8
Non-Polymers*Number of molecules9
Total formula weight626.9
All*Total formula weight66294.6
*Water molecules are not included.

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PDB entries from 2024-07-17

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