7LK0
Ornithine Aminotransferase (OAT) cocrystallized with its potent inhibitor - (S)-3-amino-4,4-difluorocyclopent-1-enecarboxylic acid (SS-1-148)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Ornithine aminotransferase, mitochondrial | polymer | 404 | 44860.3 | 3 | UniProt (P04181) Pfam (PF00202) | Homo sapiens (Human) | Ornithine delta-aminotransferase,Ornithine--oxo-acid aminotransferase |
| 2 | D, E, F (A, B, C) | (1R,3S)-3-[(E)-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)amino]-4-oxocyclopentane-1-carboxylic acid | non-polymer | 372.3 | 3 | Chemie (Y3D) | |||
| 3 | G, H, I (A, B, C) | water | water | 18.0 | 582 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 134581.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1116.8 | |
| All* | Total formula weight | 135697.8 |
