7LJ5
Human TRAAK K+ channel FHIEG mutant A198E in a K+ bound conductive conformation
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Isoform 2 of Potassium channel subfamily K member 4 | polymer | 299 | 32627.7 | 2 | UniProt (Q9NYG8-2) Pfam (PF07885) UniProt (by SIFTS) (Q9NYG8) In PDB | Homo sapiens (Human) | TWIK-related arachidonic acid-stimulated potassium channel protein,TRAAK,Two pore potassium channel KT4.1,Two pore K(+) channel KT4.1 |
2 | D, F | ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT LIGHT CHAIN | polymer | 211 | 23038.4 | 2 | Mus musculus | ||
3 | E, G | ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT HEAVY CHAIN | polymer | 217 | 23474.4 | 2 | Mus musculus | ||
4 | A, B | POTASSIUM ION | non-polymer | 39.1 | 7 | Chemie (K) | |||
5 | A, G | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
6 | water | water | 18.0 | 248 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 290 (UniProt: Q9NYG8-2)
PDB | External Database | Details |
---|---|---|
Gln 104 | Asn 104 | engineered mutation |
Gln 108 | Asn 108 | engineered mutation |
Glu 198 | Ala 198 | engineered mutation |
Ser 291 | - | expression tag |
Asn 292 | - | expression tag |
Ser 293 | - | expression tag |
Leu 294 | - | expression tag |
Glu 295 | - | expression tag |
Val 296 | - | expression tag |
Leu 297 | - | expression tag |
Phe 298 | - | expression tag |
Gln 299 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 158280.9 | |
Non-Polymers* | Number of molecules | 10 |
Total formula weight | 393.9 | |
All* | Total formula weight | 158674.9 |