7LJ1

Human Prx1-Srx Decameric Complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Peroxiredoxin-1	polymer	199	22103.2	20	UniProt (Q06830) Pfam (PF00578) Pfam (PF10417) In PDB	Homo sapiens (Human)	Natural killer cell-enhancing factor A,NKEF-A,Proliferation-associated gene protein,PAG,Thioredoxin peroxidase 2,Thioredoxin-dependent peroxide reductase 2,Thioredoxin-dependent peroxiredoxin 1
2	a, b, c, d, e...	Sulfiredoxin-1	polymer	109	11896.5	20	UniProt (Q9BYN0) In PDB	Homo sapiens (Human)
3	H, J, O, P, Q...	1,2-ETHANEDIOL	non-polymer		62.1	16	Chemie (EDO)
4	l, m, n, o, p...	PHOSPHATE ION	non-polymer		95.0	19	Chemie (PO4)
5	K, N, O, P, Q...	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	8	Chemie (PEG)
6	O, H	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
7	c, g	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	2	Chemie (ATP)
8		water	water		18.0	200	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T: 1 - 199 (UniProt: Q06830)

PDB	External Database	Details
Ser 71	Cys 71	engineered mutation
Val 83	Cys 83	engineered mutation
Ser 173	Cys 173	engineered mutation

a, b, c, d, e, f, g, h, i, j, k, l, m, n, o, p, q, r, s, t: 32 - 137 (UniProt: Q9BYN0)

PDB	External Database	Details
Gly 29	-	expression tag
Pro 30	-	expression tag
Met 31	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	40
	Total formula weight	679994.9
Non-Polymers*	Number of molecules	47
	Total formula weight	4845.0
All*	Total formula weight	684839.9

*Water molecules are not included.