7LJ1

Human Prx1-Srx Decameric Complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000302	biological_process	response to reactive oxygen species
A	0001501	biological_process	skeletal system development
A	0003723	molecular_function	RNA binding
A	0004601	molecular_function	peroxidase activity
A	0005515	molecular_function	protein binding
A	0005615	cellular_component	extracellular space
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006979	biological_process	response to oxidative stress
A	0007249	biological_process	canonical NF-kappaB signal transduction
A	0008283	biological_process	cell population proliferation
A	0008379	molecular_function	thioredoxin peroxidase activity
A	0016209	molecular_function	antioxidant activity
A	0016491	molecular_function	oxidoreductase activity
A	0019430	biological_process	removal of superoxide radicals
A	0030101	biological_process	natural killer cell activation
A	0032872	biological_process	regulation of stress-activated MAPK cascade
A	0034101	biological_process	erythrocyte homeostasis
A	0042267	biological_process	natural killer cell mediated cytotoxicity
A	0042470	cellular_component	melanosome
A	0042744	biological_process	hydrogen peroxide catabolic process
A	0042802	molecular_function	identical protein binding
A	0045296	molecular_function	cadherin binding
A	0045321	biological_process	leukocyte activation
A	0045454	biological_process	cell redox homeostasis
A	0048144	biological_process	fibroblast proliferation
A	0051920	molecular_function	peroxiredoxin activity
A	0070062	cellular_component	extracellular exosome
A	0140824	molecular_function	thioredoxin-dependent peroxiredoxin activity
A	1901222	biological_process	regulation of non-canonical NF-kappaB signal transduction
B	0000302	biological_process	response to reactive oxygen species
B	0001501	biological_process	skeletal system development
B	0003723	molecular_function	RNA binding
B	0004601	molecular_function	peroxidase activity
B	0005515	molecular_function	protein binding
B	0005615	cellular_component	extracellular space
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006979	biological_process	response to oxidative stress
B	0007249	biological_process	canonical NF-kappaB signal transduction
B	0008283	biological_process	cell population proliferation
B	0008379	molecular_function	thioredoxin peroxidase activity
B	0016209	molecular_function	antioxidant activity
B	0016491	molecular_function	oxidoreductase activity
B	0019430	biological_process	removal of superoxide radicals
B	0030101	biological_process	natural killer cell activation
B	0032872	biological_process	regulation of stress-activated MAPK cascade
B	0034101	biological_process	erythrocyte homeostasis
B	0042267	biological_process	natural killer cell mediated cytotoxicity
B	0042470	cellular_component	melanosome
B	0042744	biological_process	hydrogen peroxide catabolic process
B	0042802	molecular_function	identical protein binding
B	0045296	molecular_function	cadherin binding
B	0045321	biological_process	leukocyte activation
B	0045454	biological_process	cell redox homeostasis
B	0048144	biological_process	fibroblast proliferation
B	0051920	molecular_function	peroxiredoxin activity
B	0070062	cellular_component	extracellular exosome
B	0140824	molecular_function	thioredoxin-dependent peroxiredoxin activity
B	1901222	biological_process	regulation of non-canonical NF-kappaB signal transduction
C	0000302	biological_process	response to reactive oxygen species
C	0001501	biological_process	skeletal system development
C	0003723	molecular_function	RNA binding
C	0004601	molecular_function	peroxidase activity
C	0005515	molecular_function	protein binding
C	0005615	cellular_component	extracellular space
C	0005634	cellular_component	nucleus
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006979	biological_process	response to oxidative stress
C	0007249	biological_process	canonical NF-kappaB signal transduction
C	0008283	biological_process	cell population proliferation
C	0008379	molecular_function	thioredoxin peroxidase activity
C	0016209	molecular_function	antioxidant activity
C	0016491	molecular_function	oxidoreductase activity
C	0019430	biological_process	removal of superoxide radicals
C	0030101	biological_process	natural killer cell activation
C	0032872	biological_process	regulation of stress-activated MAPK cascade
C	0034101	biological_process	erythrocyte homeostasis
C	0042267	biological_process	natural killer cell mediated cytotoxicity
C	0042470	cellular_component	melanosome
C	0042744	biological_process	hydrogen peroxide catabolic process
C	0042802	molecular_function	identical protein binding
C	0045296	molecular_function	cadherin binding
C	0045321	biological_process	leukocyte activation
C	0045454	biological_process	cell redox homeostasis
C	0048144	biological_process	fibroblast proliferation
C	0051920	molecular_function	peroxiredoxin activity
C	0070062	cellular_component	extracellular exosome
C	0140824	molecular_function	thioredoxin-dependent peroxiredoxin activity
C	1901222	biological_process	regulation of non-canonical NF-kappaB signal transduction
D	0000302	biological_process	response to reactive oxygen species
D	0001501	biological_process	skeletal system development
D	0003723	molecular_function	RNA binding
D	0004601	molecular_function	peroxidase activity
D	0005515	molecular_function	protein binding
D	0005615	cellular_component	extracellular space
D	0005634	cellular_component	nucleus
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006979	biological_process	response to oxidative stress
D	0007249	biological_process	canonical NF-kappaB signal transduction
D	0008283	biological_process	cell population proliferation
D	0008379	molecular_function	thioredoxin peroxidase activity
D	0016209	molecular_function	antioxidant activity
D	0016491	molecular_function	oxidoreductase activity
D	0019430	biological_process	removal of superoxide radicals
D	0030101	biological_process	natural killer cell activation
D	0032872	biological_process	regulation of stress-activated MAPK cascade
D	0034101	biological_process	erythrocyte homeostasis
D	0042267	biological_process	natural killer cell mediated cytotoxicity
D	0042470	cellular_component	melanosome
D	0042744	biological_process	hydrogen peroxide catabolic process
D	0042802	molecular_function	identical protein binding
D	0045296	molecular_function	cadherin binding
D	0045321	biological_process	leukocyte activation
D	0045454	biological_process	cell redox homeostasis
D	0048144	biological_process	fibroblast proliferation
D	0051920	molecular_function	peroxiredoxin activity
D	0070062	cellular_component	extracellular exosome
D	0140824	molecular_function	thioredoxin-dependent peroxiredoxin activity
D	1901222	biological_process	regulation of non-canonical NF-kappaB signal transduction
E	0000302	biological_process	response to reactive oxygen species
E	0001501	biological_process	skeletal system development
E	0003723	molecular_function	RNA binding
E	0004601	molecular_function	peroxidase activity
E	0005515	molecular_function	protein binding
E	0005615	cellular_component	extracellular space
E	0005634	cellular_component	nucleus
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0006979	biological_process	response to oxidative stress
E	0007249	biological_process	canonical NF-kappaB signal transduction
E	0008283	biological_process	cell population proliferation
E	0008379	molecular_function	thioredoxin peroxidase activity
E	0016209	molecular_function	antioxidant activity
E	0016491	molecular_function	oxidoreductase activity
E	0019430	biological_process	removal of superoxide radicals
E	0030101	biological_process	natural killer cell activation
E	0032872	biological_process	regulation of stress-activated MAPK cascade
E	0034101	biological_process	erythrocyte homeostasis
E	0042267	biological_process	natural killer cell mediated cytotoxicity
E	0042470	cellular_component	melanosome
E	0042744	biological_process	hydrogen peroxide catabolic process
E	0042802	molecular_function	identical protein binding
E	0045296	molecular_function	cadherin binding
E	0045321	biological_process	leukocyte activation
E	0045454	biological_process	cell redox homeostasis
E	0048144	biological_process	fibroblast proliferation
E	0051920	molecular_function	peroxiredoxin activity
E	0070062	cellular_component	extracellular exosome
E	0140824	molecular_function	thioredoxin-dependent peroxiredoxin activity
E	1901222	biological_process	regulation of non-canonical NF-kappaB signal transduction
F	0000302	biological_process	response to reactive oxygen species
F	0001501	biological_process	skeletal system development
F	0003723	molecular_function	RNA binding
F	0004601	molecular_function	peroxidase activity
F	0005515	molecular_function	protein binding
F	0005615	cellular_component	extracellular space
F	0005634	cellular_component	nucleus
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0006979	biological_process	response to oxidative stress
F	0007249	biological_process	canonical NF-kappaB signal transduction
F	0008283	biological_process	cell population proliferation
F	0008379	molecular_function	thioredoxin peroxidase activity
F	0016209	molecular_function	antioxidant activity
F	0016491	molecular_function	oxidoreductase activity
F	0019430	biological_process	removal of superoxide radicals
F	0030101	biological_process	natural killer cell activation
F	0032872	biological_process	regulation of stress-activated MAPK cascade
F	0034101	biological_process	erythrocyte homeostasis
F	0042267	biological_process	natural killer cell mediated cytotoxicity
F	0042470	cellular_component	melanosome
F	0042744	biological_process	hydrogen peroxide catabolic process
F	0042802	molecular_function	identical protein binding
F	0045296	molecular_function	cadherin binding
F	0045321	biological_process	leukocyte activation
F	0045454	biological_process	cell redox homeostasis
F	0048144	biological_process	fibroblast proliferation
F	0051920	molecular_function	peroxiredoxin activity
F	0070062	cellular_component	extracellular exosome
F	0140824	molecular_function	thioredoxin-dependent peroxiredoxin activity
F	1901222	biological_process	regulation of non-canonical NF-kappaB signal transduction
G	0000302	biological_process	response to reactive oxygen species
G	0001501	biological_process	skeletal system development
G	0003723	molecular_function	RNA binding
G	0004601	molecular_function	peroxidase activity
G	0005515	molecular_function	protein binding
G	0005615	cellular_component	extracellular space
G	0005634	cellular_component	nucleus
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0006979	biological_process	response to oxidative stress
G	0007249	biological_process	canonical NF-kappaB signal transduction
G	0008283	biological_process	cell population proliferation
G	0008379	molecular_function	thioredoxin peroxidase activity
G	0016209	molecular_function	antioxidant activity
G	0016491	molecular_function	oxidoreductase activity
G	0019430	biological_process	removal of superoxide radicals
G	0030101	biological_process	natural killer cell activation
G	0032872	biological_process	regulation of stress-activated MAPK cascade
G	0034101	biological_process	erythrocyte homeostasis
G	0042267	biological_process	natural killer cell mediated cytotoxicity
G	0042470	cellular_component	melanosome
G	0042744	biological_process	hydrogen peroxide catabolic process
G	0042802	molecular_function	identical protein binding
G	0045296	molecular_function	cadherin binding
G	0045321	biological_process	leukocyte activation
G	0045454	biological_process	cell redox homeostasis
G	0048144	biological_process	fibroblast proliferation
G	0051920	molecular_function	peroxiredoxin activity
G	0070062	cellular_component	extracellular exosome
G	0140824	molecular_function	thioredoxin-dependent peroxiredoxin activity
G	1901222	biological_process	regulation of non-canonical NF-kappaB signal transduction
H	0000302	biological_process	response to reactive oxygen species
H	0001501	biological_process	skeletal system development
H	0003723	molecular_function	RNA binding
H	0004601	molecular_function	peroxidase activity
H	0005515	molecular_function	protein binding
H	0005615	cellular_component	extracellular space
H	0005634	cellular_component	nucleus
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0006979	biological_process	response to oxidative stress
H	0007249	biological_process	canonical NF-kappaB signal transduction
H	0008283	biological_process	cell population proliferation
H	0008379	molecular_function	thioredoxin peroxidase activity
H	0016209	molecular_function	antioxidant activity
H	0016491	molecular_function	oxidoreductase activity
H	0019430	biological_process	removal of superoxide radicals
H	0030101	biological_process	natural killer cell activation
H	0032872	biological_process	regulation of stress-activated MAPK cascade
H	0034101	biological_process	erythrocyte homeostasis
H	0042267	biological_process	natural killer cell mediated cytotoxicity
H	0042470	cellular_component	melanosome
H	0042744	biological_process	hydrogen peroxide catabolic process
H	0042802	molecular_function	identical protein binding
H	0045296	molecular_function	cadherin binding
H	0045321	biological_process	leukocyte activation
H	0045454	biological_process	cell redox homeostasis
H	0048144	biological_process	fibroblast proliferation
H	0051920	molecular_function	peroxiredoxin activity
H	0070062	cellular_component	extracellular exosome
H	0140824	molecular_function	thioredoxin-dependent peroxiredoxin activity
H	1901222	biological_process	regulation of non-canonical NF-kappaB signal transduction
I	0000302	biological_process	response to reactive oxygen species
I	0001501	biological_process	skeletal system development
I	0003723	molecular_function	RNA binding
I	0004601	molecular_function	peroxidase activity
I	0005515	molecular_function	protein binding
I	0005615	cellular_component	extracellular space
I	0005634	cellular_component	nucleus
I	0005737	cellular_component	cytoplasm
I	0005829	cellular_component	cytosol
I	0006979	biological_process	response to oxidative stress
I	0007249	biological_process	canonical NF-kappaB signal transduction
I	0008283	biological_process	cell population proliferation
I	0008379	molecular_function	thioredoxin peroxidase activity
I	0016209	molecular_function	antioxidant activity
I	0016491	molecular_function	oxidoreductase activity
I	0019430	biological_process	removal of superoxide radicals
I	0030101	biological_process	natural killer cell activation
I	0032872	biological_process	regulation of stress-activated MAPK cascade
I	0034101	biological_process	erythrocyte homeostasis
I	0042267	biological_process	natural killer cell mediated cytotoxicity
I	0042470	cellular_component	melanosome
I	0042744	biological_process	hydrogen peroxide catabolic process
I	0042802	molecular_function	identical protein binding
I	0045296	molecular_function	cadherin binding
I	0045321	biological_process	leukocyte activation
I	0045454	biological_process	cell redox homeostasis
I	0048144	biological_process	fibroblast proliferation
I	0051920	molecular_function	peroxiredoxin activity
I	0070062	cellular_component	extracellular exosome
I	0140824	molecular_function	thioredoxin-dependent peroxiredoxin activity
I	1901222	biological_process	regulation of non-canonical NF-kappaB signal transduction
J	0000302	biological_process	response to reactive oxygen species
J	0001501	biological_process	skeletal system development
J	0003723	molecular_function	RNA binding
J	0004601	molecular_function	peroxidase activity
J	0005515	molecular_function	protein binding
J	0005615	cellular_component	extracellular space
J	0005634	cellular_component	nucleus
J	0005737	cellular_component	cytoplasm
J	0005829	cellular_component	cytosol
J	0006979	biological_process	response to oxidative stress
J	0007249	biological_process	canonical NF-kappaB signal transduction
J	0008283	biological_process	cell population proliferation
J	0008379	molecular_function	thioredoxin peroxidase activity
J	0016209	molecular_function	antioxidant activity
J	0016491	molecular_function	oxidoreductase activity
J	0019430	biological_process	removal of superoxide radicals
J	0030101	biological_process	natural killer cell activation
J	0032872	biological_process	regulation of stress-activated MAPK cascade
J	0034101	biological_process	erythrocyte homeostasis
J	0042267	biological_process	natural killer cell mediated cytotoxicity
J	0042470	cellular_component	melanosome
J	0042744	biological_process	hydrogen peroxide catabolic process
J	0042802	molecular_function	identical protein binding
J	0045296	molecular_function	cadherin binding
J	0045321	biological_process	leukocyte activation
J	0045454	biological_process	cell redox homeostasis
J	0048144	biological_process	fibroblast proliferation
J	0051920	molecular_function	peroxiredoxin activity
J	0070062	cellular_component	extracellular exosome
J	0140824	molecular_function	thioredoxin-dependent peroxiredoxin activity
J	1901222	biological_process	regulation of non-canonical NF-kappaB signal transduction
K	0000302	biological_process	response to reactive oxygen species
K	0001501	biological_process	skeletal system development
K	0003723	molecular_function	RNA binding
K	0004601	molecular_function	peroxidase activity
K	0005515	molecular_function	protein binding
K	0005615	cellular_component	extracellular space
K	0005634	cellular_component	nucleus
K	0005737	cellular_component	cytoplasm
K	0005829	cellular_component	cytosol
K	0006979	biological_process	response to oxidative stress
K	0007249	biological_process	canonical NF-kappaB signal transduction
K	0008283	biological_process	cell population proliferation
K	0008379	molecular_function	thioredoxin peroxidase activity
K	0016209	molecular_function	antioxidant activity
K	0016491	molecular_function	oxidoreductase activity
K	0019430	biological_process	removal of superoxide radicals
K	0030101	biological_process	natural killer cell activation
K	0032872	biological_process	regulation of stress-activated MAPK cascade
K	0034101	biological_process	erythrocyte homeostasis
K	0042267	biological_process	natural killer cell mediated cytotoxicity
K	0042470	cellular_component	melanosome
K	0042744	biological_process	hydrogen peroxide catabolic process
K	0042802	molecular_function	identical protein binding
K	0045296	molecular_function	cadherin binding
K	0045321	biological_process	leukocyte activation
K	0045454	biological_process	cell redox homeostasis
K	0048144	biological_process	fibroblast proliferation
K	0051920	molecular_function	peroxiredoxin activity
K	0070062	cellular_component	extracellular exosome
K	0140824	molecular_function	thioredoxin-dependent peroxiredoxin activity
K	1901222	biological_process	regulation of non-canonical NF-kappaB signal transduction
L	0000302	biological_process	response to reactive oxygen species
L	0001501	biological_process	skeletal system development
L	0003723	molecular_function	RNA binding
L	0004601	molecular_function	peroxidase activity
L	0005515	molecular_function	protein binding
L	0005615	cellular_component	extracellular space
L	0005634	cellular_component	nucleus
L	0005737	cellular_component	cytoplasm
L	0005829	cellular_component	cytosol
L	0006979	biological_process	response to oxidative stress
L	0007249	biological_process	canonical NF-kappaB signal transduction
L	0008283	biological_process	cell population proliferation
L	0008379	molecular_function	thioredoxin peroxidase activity
L	0016209	molecular_function	antioxidant activity
L	0016491	molecular_function	oxidoreductase activity
L	0019430	biological_process	removal of superoxide radicals
L	0030101	biological_process	natural killer cell activation
L	0032872	biological_process	regulation of stress-activated MAPK cascade
L	0034101	biological_process	erythrocyte homeostasis
L	0042267	biological_process	natural killer cell mediated cytotoxicity
L	0042470	cellular_component	melanosome
L	0042744	biological_process	hydrogen peroxide catabolic process
L	0042802	molecular_function	identical protein binding
L	0045296	molecular_function	cadherin binding
L	0045321	biological_process	leukocyte activation
L	0045454	biological_process	cell redox homeostasis
L	0048144	biological_process	fibroblast proliferation
L	0051920	molecular_function	peroxiredoxin activity
L	0070062	cellular_component	extracellular exosome
L	0140824	molecular_function	thioredoxin-dependent peroxiredoxin activity
L	1901222	biological_process	regulation of non-canonical NF-kappaB signal transduction
M	0000302	biological_process	response to reactive oxygen species
M	0001501	biological_process	skeletal system development
M	0003723	molecular_function	RNA binding
M	0004601	molecular_function	peroxidase activity
M	0005515	molecular_function	protein binding
M	0005615	cellular_component	extracellular space
M	0005634	cellular_component	nucleus
M	0005737	cellular_component	cytoplasm
M	0005829	cellular_component	cytosol
M	0006979	biological_process	response to oxidative stress
M	0007249	biological_process	canonical NF-kappaB signal transduction
M	0008283	biological_process	cell population proliferation
M	0008379	molecular_function	thioredoxin peroxidase activity
M	0016209	molecular_function	antioxidant activity
M	0016491	molecular_function	oxidoreductase activity
M	0019430	biological_process	removal of superoxide radicals
M	0030101	biological_process	natural killer cell activation
M	0032872	biological_process	regulation of stress-activated MAPK cascade
M	0034101	biological_process	erythrocyte homeostasis
M	0042267	biological_process	natural killer cell mediated cytotoxicity
M	0042470	cellular_component	melanosome
M	0042744	biological_process	hydrogen peroxide catabolic process
M	0042802	molecular_function	identical protein binding
M	0045296	molecular_function	cadherin binding
M	0045321	biological_process	leukocyte activation
M	0045454	biological_process	cell redox homeostasis
M	0048144	biological_process	fibroblast proliferation
M	0051920	molecular_function	peroxiredoxin activity
M	0070062	cellular_component	extracellular exosome
M	0140824	molecular_function	thioredoxin-dependent peroxiredoxin activity
M	1901222	biological_process	regulation of non-canonical NF-kappaB signal transduction
N	0000302	biological_process	response to reactive oxygen species
N	0001501	biological_process	skeletal system development
N	0003723	molecular_function	RNA binding
N	0004601	molecular_function	peroxidase activity
N	0005515	molecular_function	protein binding
N	0005615	cellular_component	extracellular space
N	0005634	cellular_component	nucleus
N	0005737	cellular_component	cytoplasm
N	0005829	cellular_component	cytosol
N	0006979	biological_process	response to oxidative stress
N	0007249	biological_process	canonical NF-kappaB signal transduction
N	0008283	biological_process	cell population proliferation
N	0008379	molecular_function	thioredoxin peroxidase activity
N	0016209	molecular_function	antioxidant activity
N	0016491	molecular_function	oxidoreductase activity
N	0019430	biological_process	removal of superoxide radicals
N	0030101	biological_process	natural killer cell activation
N	0032872	biological_process	regulation of stress-activated MAPK cascade
N	0034101	biological_process	erythrocyte homeostasis
N	0042267	biological_process	natural killer cell mediated cytotoxicity
N	0042470	cellular_component	melanosome
N	0042744	biological_process	hydrogen peroxide catabolic process
N	0042802	molecular_function	identical protein binding
N	0045296	molecular_function	cadherin binding
N	0045321	biological_process	leukocyte activation
N	0045454	biological_process	cell redox homeostasis
N	0048144	biological_process	fibroblast proliferation
N	0051920	molecular_function	peroxiredoxin activity
N	0070062	cellular_component	extracellular exosome
N	0140824	molecular_function	thioredoxin-dependent peroxiredoxin activity
N	1901222	biological_process	regulation of non-canonical NF-kappaB signal transduction
O	0000302	biological_process	response to reactive oxygen species
O	0001501	biological_process	skeletal system development
O	0003723	molecular_function	RNA binding
O	0004601	molecular_function	peroxidase activity
O	0005515	molecular_function	protein binding
O	0005615	cellular_component	extracellular space
O	0005634	cellular_component	nucleus
O	0005737	cellular_component	cytoplasm
O	0005829	cellular_component	cytosol
O	0006979	biological_process	response to oxidative stress
O	0007249	biological_process	canonical NF-kappaB signal transduction
O	0008283	biological_process	cell population proliferation
O	0008379	molecular_function	thioredoxin peroxidase activity
O	0016209	molecular_function	antioxidant activity
O	0016491	molecular_function	oxidoreductase activity
O	0019430	biological_process	removal of superoxide radicals
O	0030101	biological_process	natural killer cell activation
O	0032872	biological_process	regulation of stress-activated MAPK cascade
O	0034101	biological_process	erythrocyte homeostasis
O	0042267	biological_process	natural killer cell mediated cytotoxicity
O	0042470	cellular_component	melanosome
O	0042744	biological_process	hydrogen peroxide catabolic process
O	0042802	molecular_function	identical protein binding
O	0045296	molecular_function	cadherin binding
O	0045321	biological_process	leukocyte activation
O	0045454	biological_process	cell redox homeostasis
O	0048144	biological_process	fibroblast proliferation
O	0051920	molecular_function	peroxiredoxin activity
O	0070062	cellular_component	extracellular exosome
O	0140824	molecular_function	thioredoxin-dependent peroxiredoxin activity
O	1901222	biological_process	regulation of non-canonical NF-kappaB signal transduction
P	0000302	biological_process	response to reactive oxygen species
P	0001501	biological_process	skeletal system development
P	0003723	molecular_function	RNA binding
P	0004601	molecular_function	peroxidase activity
P	0005515	molecular_function	protein binding
P	0005615	cellular_component	extracellular space
P	0005634	cellular_component	nucleus
P	0005737	cellular_component	cytoplasm
P	0005829	cellular_component	cytosol
P	0006979	biological_process	response to oxidative stress
P	0007249	biological_process	canonical NF-kappaB signal transduction
P	0008283	biological_process	cell population proliferation
P	0008379	molecular_function	thioredoxin peroxidase activity
P	0016209	molecular_function	antioxidant activity
P	0016491	molecular_function	oxidoreductase activity
P	0019430	biological_process	removal of superoxide radicals
P	0030101	biological_process	natural killer cell activation
P	0032872	biological_process	regulation of stress-activated MAPK cascade
P	0034101	biological_process	erythrocyte homeostasis
P	0042267	biological_process	natural killer cell mediated cytotoxicity
P	0042470	cellular_component	melanosome
P	0042744	biological_process	hydrogen peroxide catabolic process
P	0042802	molecular_function	identical protein binding
P	0045296	molecular_function	cadherin binding
P	0045321	biological_process	leukocyte activation
P	0045454	biological_process	cell redox homeostasis
P	0048144	biological_process	fibroblast proliferation
P	0051920	molecular_function	peroxiredoxin activity
P	0070062	cellular_component	extracellular exosome
P	0140824	molecular_function	thioredoxin-dependent peroxiredoxin activity
P	1901222	biological_process	regulation of non-canonical NF-kappaB signal transduction
Q	0000302	biological_process	response to reactive oxygen species
Q	0001501	biological_process	skeletal system development
Q	0003723	molecular_function	RNA binding
Q	0004601	molecular_function	peroxidase activity
Q	0005515	molecular_function	protein binding
Q	0005615	cellular_component	extracellular space
Q	0005634	cellular_component	nucleus
Q	0005737	cellular_component	cytoplasm
Q	0005829	cellular_component	cytosol
Q	0006979	biological_process	response to oxidative stress
Q	0007249	biological_process	canonical NF-kappaB signal transduction
Q	0008283	biological_process	cell population proliferation
Q	0008379	molecular_function	thioredoxin peroxidase activity
Q	0016209	molecular_function	antioxidant activity
Q	0016491	molecular_function	oxidoreductase activity
Q	0019430	biological_process	removal of superoxide radicals
Q	0030101	biological_process	natural killer cell activation
Q	0032872	biological_process	regulation of stress-activated MAPK cascade
Q	0034101	biological_process	erythrocyte homeostasis
Q	0042267	biological_process	natural killer cell mediated cytotoxicity
Q	0042470	cellular_component	melanosome
Q	0042744	biological_process	hydrogen peroxide catabolic process
Q	0042802	molecular_function	identical protein binding
Q	0045296	molecular_function	cadherin binding
Q	0045321	biological_process	leukocyte activation
Q	0045454	biological_process	cell redox homeostasis
Q	0048144	biological_process	fibroblast proliferation
Q	0051920	molecular_function	peroxiredoxin activity
Q	0070062	cellular_component	extracellular exosome
Q	0140824	molecular_function	thioredoxin-dependent peroxiredoxin activity
Q	1901222	biological_process	regulation of non-canonical NF-kappaB signal transduction
R	0000302	biological_process	response to reactive oxygen species
R	0001501	biological_process	skeletal system development
R	0003723	molecular_function	RNA binding
R	0004601	molecular_function	peroxidase activity
R	0005515	molecular_function	protein binding
R	0005615	cellular_component	extracellular space
R	0005634	cellular_component	nucleus
R	0005737	cellular_component	cytoplasm
R	0005829	cellular_component	cytosol
R	0006979	biological_process	response to oxidative stress
R	0007249	biological_process	canonical NF-kappaB signal transduction
R	0008283	biological_process	cell population proliferation
R	0008379	molecular_function	thioredoxin peroxidase activity
R	0016209	molecular_function	antioxidant activity
R	0016491	molecular_function	oxidoreductase activity
R	0019430	biological_process	removal of superoxide radicals
R	0030101	biological_process	natural killer cell activation
R	0032872	biological_process	regulation of stress-activated MAPK cascade
R	0034101	biological_process	erythrocyte homeostasis
R	0042267	biological_process	natural killer cell mediated cytotoxicity
R	0042470	cellular_component	melanosome
R	0042744	biological_process	hydrogen peroxide catabolic process
R	0042802	molecular_function	identical protein binding
R	0045296	molecular_function	cadherin binding
R	0045321	biological_process	leukocyte activation
R	0045454	biological_process	cell redox homeostasis
R	0048144	biological_process	fibroblast proliferation
R	0051920	molecular_function	peroxiredoxin activity
R	0070062	cellular_component	extracellular exosome
R	0140824	molecular_function	thioredoxin-dependent peroxiredoxin activity
R	1901222	biological_process	regulation of non-canonical NF-kappaB signal transduction
S	0000302	biological_process	response to reactive oxygen species
S	0001501	biological_process	skeletal system development
S	0003723	molecular_function	RNA binding
S	0004601	molecular_function	peroxidase activity
S	0005515	molecular_function	protein binding
S	0005615	cellular_component	extracellular space
S	0005634	cellular_component	nucleus
S	0005737	cellular_component	cytoplasm
S	0005829	cellular_component	cytosol
S	0006979	biological_process	response to oxidative stress
S	0007249	biological_process	canonical NF-kappaB signal transduction
S	0008283	biological_process	cell population proliferation
S	0008379	molecular_function	thioredoxin peroxidase activity
S	0016209	molecular_function	antioxidant activity
S	0016491	molecular_function	oxidoreductase activity
S	0019430	biological_process	removal of superoxide radicals
S	0030101	biological_process	natural killer cell activation
S	0032872	biological_process	regulation of stress-activated MAPK cascade
S	0034101	biological_process	erythrocyte homeostasis
S	0042267	biological_process	natural killer cell mediated cytotoxicity
S	0042470	cellular_component	melanosome
S	0042744	biological_process	hydrogen peroxide catabolic process
S	0042802	molecular_function	identical protein binding
S	0045296	molecular_function	cadherin binding
S	0045321	biological_process	leukocyte activation
S	0045454	biological_process	cell redox homeostasis
S	0048144	biological_process	fibroblast proliferation
S	0051920	molecular_function	peroxiredoxin activity
S	0070062	cellular_component	extracellular exosome
S	0140824	molecular_function	thioredoxin-dependent peroxiredoxin activity
S	1901222	biological_process	regulation of non-canonical NF-kappaB signal transduction
T	0000302	biological_process	response to reactive oxygen species
T	0001501	biological_process	skeletal system development
T	0003723	molecular_function	RNA binding
T	0004601	molecular_function	peroxidase activity
T	0005515	molecular_function	protein binding
T	0005615	cellular_component	extracellular space
T	0005634	cellular_component	nucleus
T	0005737	cellular_component	cytoplasm
T	0005829	cellular_component	cytosol
T	0006979	biological_process	response to oxidative stress
T	0007249	biological_process	canonical NF-kappaB signal transduction
T	0008283	biological_process	cell population proliferation
T	0008379	molecular_function	thioredoxin peroxidase activity
T	0016209	molecular_function	antioxidant activity
T	0016491	molecular_function	oxidoreductase activity
T	0019430	biological_process	removal of superoxide radicals
T	0030101	biological_process	natural killer cell activation
T	0032872	biological_process	regulation of stress-activated MAPK cascade
T	0034101	biological_process	erythrocyte homeostasis
T	0042267	biological_process	natural killer cell mediated cytotoxicity
T	0042470	cellular_component	melanosome
T	0042744	biological_process	hydrogen peroxide catabolic process
T	0042802	molecular_function	identical protein binding
T	0045296	molecular_function	cadherin binding
T	0045321	biological_process	leukocyte activation
T	0045454	biological_process	cell redox homeostasis
T	0048144	biological_process	fibroblast proliferation
T	0051920	molecular_function	peroxiredoxin activity
T	0070062	cellular_component	extracellular exosome
T	0140824	molecular_function	thioredoxin-dependent peroxiredoxin activity
T	1901222	biological_process	regulation of non-canonical NF-kappaB signal transduction
a	0032542	molecular_function	sulfiredoxin activity
b	0032542	molecular_function	sulfiredoxin activity
c	0032542	molecular_function	sulfiredoxin activity
d	0032542	molecular_function	sulfiredoxin activity
e	0032542	molecular_function	sulfiredoxin activity
f	0032542	molecular_function	sulfiredoxin activity
g	0032542	molecular_function	sulfiredoxin activity
h	0032542	molecular_function	sulfiredoxin activity
i	0032542	molecular_function	sulfiredoxin activity
j	0032542	molecular_function	sulfiredoxin activity
k	0032542	molecular_function	sulfiredoxin activity
l	0032542	molecular_function	sulfiredoxin activity
m	0032542	molecular_function	sulfiredoxin activity
n	0032542	molecular_function	sulfiredoxin activity
o	0032542	molecular_function	sulfiredoxin activity
p	0032542	molecular_function	sulfiredoxin activity
q	0032542	molecular_function	sulfiredoxin activity
r	0032542	molecular_function	sulfiredoxin activity
s	0032542	molecular_function	sulfiredoxin activity
t	0032542	molecular_function	sulfiredoxin activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	20
Details	BINDING: BINDING => ECO:0000269|PubMed:15952770

Chain	Residue	Details
a	GLY98
b	GLY98
c	GLY98
d	GLY98
e	GLY98
f	GLY98
g	GLY98
h	GLY98
i	GLY98
j	GLY98
k	GLY98
l	GLY98
m	GLY98
n	GLY98
o	GLY98
p	GLY98
q	GLY98
r	GLY98
s	GLY98
t	GLY98

---

site_id	SWS_FT_FI2
Number of Residues	20
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
b	SER32
c	SER32
d	SER32
e	SER32
f	SER32
g	SER32
h	SER32
i	SER32
j	SER32
k	SER32
l	SER32
m	SER32
n	SER32
o	SER32
p	SER32
q	SER32
r	SER32
s	SER32
t	SER32
a	SER32

---

site_id	SWS_FT_FI3
Number of Residues	20
Details	MOD_RES: N6-acetyllysine; alternate => ECO:0007744|PubMed:19608861

Chain	Residue	Details
B	LYS7
C	LYS7
D	LYS7
E	LYS7
F	LYS7
G	LYS7
H	LYS7
I	LYS7
J	LYS7
K	LYS7
L	LYS7
M	LYS7
N	LYS7
O	LYS7
P	LYS7
Q	LYS7
R	LYS7
S	LYS7
T	LYS7
A	LYS7

---

site_id	SWS_FT_FI4
Number of Residues	40
Details	MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861

Chain	Residue	Details
B	LYS27
C	LYS16
C	LYS27
D	LYS16
D	LYS27
I	LYS16
I	LYS27
J	LYS16
J	LYS27
Q	LYS27
R	LYS16
R	LYS27
B	LYS16
E	LYS16
E	LYS27
F	LYS16
F	LYS27
G	LYS16
G	LYS27
H	LYS16
H	LYS27
K	LYS16
K	LYS27
L	LYS16
L	LYS27
M	LYS16
M	LYS27
N	LYS16
N	LYS27
O	LYS16
O	LYS27
P	LYS16
P	LYS27
Q	LYS16
S	LYS16
S	LYS27
T	LYS16
T	LYS27
A	LYS16
A	LYS27

---

site_id	SWS_FT_FI5
Number of Residues	20
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
B	SER32
C	SER32
D	SER32
E	SER32
F	SER32
G	SER32
H	SER32
I	SER32
J	SER32
K	SER32
L	SER32
M	SER32
N	SER32
O	SER32
P	SER32
Q	SER32
R	SER32
S	SER32
T	SER32
A	SER32

---

site_id	SWS_FT_FI6
Number of Residues	20
Details	MOD_RES: N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P35700

Chain	Residue	Details
B	LYS35
C	LYS35
D	LYS35
E	LYS35
F	LYS35
G	LYS35
H	LYS35
I	LYS35
J	LYS35
K	LYS35
L	LYS35
M	LYS35
N	LYS35
O	LYS35
P	LYS35
Q	LYS35
R	LYS35
S	LYS35
T	LYS35
A	LYS35

---

site_id	SWS_FT_FI7
Number of Residues	20
Details	MOD_RES: Phosphothreonine; by CDK1 => ECO:0000269|PubMed:11986303

Chain	Residue	Details
B	THR90
C	THR90
D	THR90
E	THR90
F	THR90
G	THR90
H	THR90
I	THR90
J	THR90
K	THR90
L	THR90
M	THR90
N	THR90
O	THR90
P	THR90
Q	THR90
R	THR90
S	THR90
T	THR90
A	THR90

---

site_id	SWS_FT_FI8
Number of Residues	20
Details	MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P35700

Chain	Residue	Details
B	LYS136
C	LYS136
F	LYS136
G	LYS136
H	LYS136
I	LYS136
L	LYS136
M	LYS136
N	LYS136
O	LYS136
P	LYS136
Q	LYS136
S	LYS136
T	LYS136
A	LYS136
D	LYS136
E	LYS136
J	LYS136
K	LYS136
R	LYS136

---

site_id	SWS_FT_FI9
Number of Residues	20
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:28112733

Chain	Residue	Details
B	LYS7
F	LYS7
H	LYS7
L	LYS7
N	LYS7
P	LYS7
T	LYS7
A	LYS7
C	LYS7
E	LYS7
G	LYS7
I	LYS7
K	LYS7
M	LYS7
O	LYS7
Q	LYS7
S	LYS7
D	LYS7
J	LYS7
R	LYS7

---

site_id	SWS_FT_FI10
Number of Residues	40
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1) => ECO:0007744|PubMed:25114211

Chain	Residue	Details
A	LYS185
B	LYS185
C	LYS185
D	LYS185
F	LYS185
G	LYS185
K	LYS185
L	LYS185
M	LYS185
N	LYS185
O	LYS185
P	LYS185
Q	LYS185
R	LYS185
S	LYS185
T	LYS185
E	LYS185
H	LYS185
I	LYS185
J	LYS185

---

site_id	SWS_FT_FI11
Number of Residues	20
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733

Chain	Residue	Details
A	LYS120
B	LYS120
C	LYS120
D	LYS120
E	LYS120
F	LYS120
G	LYS120
H	LYS120
I	LYS120
J	LYS120
K	LYS120
L	LYS120
M	LYS120
N	LYS120
O	LYS120
P	LYS120
Q	LYS120
R	LYS120
S	LYS120
T	LYS120

---