7LIU
DDX3X bound to ATP analog and remodeled RNA:DNA hybrid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | ATP-dependent RNA helicase DDX3X | polymer | 450 | 50817.8 | 2 | UniProt (O00571) Pfam (PF00270) Pfam (PF00271) | Homo sapiens (Human) | CAP-Rf,DEAD box protein 3,X-chromosomal,DEAD box,X isoform,DBX,Helicase-like protein 2,HLP2 |
| 2 | C, D (X, Y) | 5'-R(*GP*GP*GP*CP*GP*GP*G)-D(P*CP*CP*CP*GP*CP*CP*C)-3' | polymer | 14 | 4395.8 | 2 | synthetic construct | ||
| 3 | E, G (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | F, H (A, B) | [[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-tris(fluoranyl)beryllium | non-polymer | 492.2 | 2 | Chemie (08T) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 8 | Chemie (HOH) |
Sequence modifications
A, B: 135 - 582 (UniProt: O00571)
| PDB | External Database | Details |
|---|---|---|
| Gly 133 | - | expression tag |
| Ser 134 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 110427.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1033.0 | |
| All* | Total formula weight | 111460.1 |
