7LHS

Crystal structure of adenosine-5'-phosphosulfate reductase from Mycobacterium tuberculosis in a complex with substrate APS

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Phosphoadenosine phosphosulfate reductase	polymer	262	28525.1	2	UniProt (A5U586) Pfam (PF01507) UniProt (by SIFTS) (P9WIK3)	Mycobacterium tuberculosis	3'-phosphoadenylylsulfate reductase,PAPS reductase,thioredoxin dependent,PAPS sulfotransferase,PAdoPS reductase, adenosine-5'-phosphosulfate reductase
2	C, F (A, B)	IRON/SULFUR CLUSTER	non-polymer		351.6	2	Chemie (SF4)
3	D, G (A, B)	2-(N-MORPHOLINO)-ETHANESULFONIC ACID	non-polymer		195.2	2	Chemie (MES)
4	E, H (A, B)	ADENOSINE-5'-PHOSPHOSULFATE	non-polymer		427.3	2	Chemie (ADX)
5	I, J (A, B)	water	water		18.0	6	Chemie (HOH)

Sequence modifications

A, B: 1 - 254 (UniProt: A5U586)

PDB	External Database	Details
Leu 255	-	expression tag
Glu 256	-	expression tag
His 257	-	expression tag
His 258	-	expression tag
His 259	-	expression tag
His 260	-	expression tag
His 261	-	expression tag
His 262	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	57050.1
Non-Polymers*	Number of molecules	6
	Total formula weight	1948.3
All*	Total formula weight	58998.5

*Water molecules are not included.