7LF7
Fab 6D12 bound to ApoL1 NTD
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Fab 6D12 heavy chain | polymer | 225 | 24262.2 | 1 | Homo sapiens (Human) | ||
| 2 | B, E (B, L) | Fab 6D12 light chain | polymer | 214 | 23568.3 | 2 | Homo sapiens (Human) | ||
| 3 | C (H) | Fab 6D12 heavy chain | polymer | 225 | 24278.2 | 1 | Homo sapiens (Human) | ||
| 4 | D, F (K, M) | Apolipoprotein L1 | polymer | 130 | 15289.1 | 2 | UniProt (O14791) | Homo sapiens (Human) | Apolipoprotein L,ApoL,Apolipoprotein L-I,ApoL-I |
| 5 | G, J (B, L) | ETHANOL | non-polymer | 46.1 | 2 | Chemie (EOH) | |||
| 6 | H, I, K, L (K, M) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 7 | M, N, O, P, Q... (A, B, H, K, L...) | water | water | 18.0 | 345 | Chemie (HOH) |
Sequence modifications
K, M: 61 - 172 (UniProt: O14791)
| PDB | External Database | Details |
|---|---|---|
| Met 43 | - | initiating methionine |
| Asp 44 | - | expression tag |
| Tyr 45 | - | expression tag |
| Lys 46 | - | expression tag |
| Asp 47 | - | expression tag |
| Asp 48 | - | expression tag |
| Asp 49 | - | expression tag |
| Asp 50 | - | expression tag |
| Lys 51 | - | expression tag |
| Gly 52 | - | expression tag |
| Glu 53 | - | expression tag |
| Asn 54 | - | expression tag |
| Leu 55 | - | expression tag |
| Tyr 56 | - | expression tag |
| Phe 57 | - | expression tag |
| Gln 58 | - | expression tag |
| Gly 59 | - | expression tag |
| Ser 60 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 126255.2 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 460.5 | |
| All* | Total formula weight | 126715.8 |
