7LF7

Fab 6D12 bound to ApoL1 NTD

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Fab 6D12 heavy chain	polymer	225	24262.2	1		Homo sapiens (Human)
2	B, L	Fab 6D12 light chain	polymer	214	23568.3	2		Homo sapiens (Human)
3	H	Fab 6D12 heavy chain	polymer	225	24278.2	1		Homo sapiens (Human)
4	K, M	Apolipoprotein L1	polymer	130	15289.1	2	UniProt (O14791) In PDB	Homo sapiens (Human)	Apolipoprotein L,ApoL,Apolipoprotein L-I,ApoL-I
5	B, L	ETHANOL	non-polymer		46.1	2	Chemie (EOH)
6	K, M	GLYCEROL	non-polymer		92.1	4	Chemie (GOL)
7		water	water		18.0	345	Chemie (HOH)

Sequence modifications

K, M: 61 - 172 (UniProt: O14791)

PDB	External Database	Details
Met 43	-	initiating methionine
Asp 44	-	expression tag
Tyr 45	-	expression tag
Lys 46	-	expression tag
Asp 47	-	expression tag
Asp 48	-	expression tag
Asp 49	-	expression tag
Asp 50	-	expression tag
Lys 51	-	expression tag
Gly 52	-	expression tag
Glu 53	-	expression tag
Asn 54	-	expression tag
Leu 55	-	expression tag
Tyr 56	-	expression tag
Phe 57	-	expression tag
Gln 58	-	expression tag
Gly 59	-	expression tag
Ser 60	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	126255.2
Non-Polymers*	Number of molecules	6
	Total formula weight	460.5
All*	Total formula weight	126715.8

*Water molecules are not included.