7LF5
Structure of Hyperglycosylated Human IgG1 Fc (Fc267)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | IgG1 Fc (Fc267) | polymer | 233 | 26163.6 | 1 | UniProt (Q6MZV7) Pfam (PF07654) In PDB | Homo sapiens (Human) | |
| 2 | B | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 3 | C | beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1479.3 | 1 | In PDB GlyTouCan (G89993FE) | |||
| 4 | A | alpha-L-fucopyranose | non-polymer | 164.2 | 1 | Chemie (FUC) | |||
| 5 | water | water | 18.0 | 2 | Chemie (HOH) |
Sequence modifications
A: 216 - 447 (UniProt: Q6MZV7)
| PDB | External Database | Details |
|---|---|---|
| Gly 215 | - | expression tag |
| Asn 267 | Ser 293 | conflict |
| Ser 268 | His 294 | conflict |
| Thr 269 | Glu 295 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 26163.6 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1903.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 164.2 | |
| All* | Total formula weight | 28231.6 |
