7LD9
Structure of human GGT1 in complex with ABBA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Glutathione hydrolase 1 heavy chain | polymer | 353 | 38533.7 | 1 | UniProt (P19440) Pfam (PF01019) | Homo sapiens (Human) | GGT 1,Gamma-glutamyltransferase 1,Glutathione hydrolase 1,Leukotriene-C4 hydrolase |
| 2 | B (B) | Glutathione hydrolase 1 light chain | polymer | 189 | 20014.4 | 1 | UniProt (P19440) Pfam (PF01019) | Homo sapiens (Human) | GGT 1,Gamma-glutamyltransferase 1,Glutathione hydrolase 1,Leukotriene-C4 hydrolase |
| 3 | C, D, E, F, G... (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) | |||
| 4 | H, L (A, B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 5 | I (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 6 | J, O, P (A, B) | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 3 | Chemie (EPE) | |||
| 7 | M (B) | (2R)-2-amino-4-boronobutanoic acid | non-polymer | 146.9 | 1 | Chemie (XUJ) | |||
| 8 | N (B) | (2S)-2-amino-4-boronobutanoic acid | non-polymer | 146.9 | 1 | Chemie (XU7) | |||
| 9 | Q, R (A, B) | water | water | 18.0 | 735 | Chemie (HOH) |
Sequence modifications
A: 28 - 380 (UniProt: P19440)
| PDB | External Database | Details |
|---|---|---|
| Ala 272 | Val 272 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 58548.1 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 2429.9 | |
| All* | Total formula weight | 60978.0 |
