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7LBQ

Crystal structure of human Survivin bound to histone H3 T3phK4me2 peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Baculoviral IAP repeat-containing protein 5polymer14616826.11UniProt (O15392)
Pfam (PF00653)
Homo sapiens (Human)Apoptosis inhibitor 4,Apoptosis inhibitor survivin
2B
(E)
histone H3 T3phK4me2 peptidepolymer121415.51UniProt (P68431)Homo sapiensHistone H3/a,Histone H3/b,Histone H3/c,Histone H3/d,Histone H3/f,Histone H3/h,Histone H3/i,Histone H3/j,Histone H3/k,Histone H3/l
3C
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
4D
(A)
waterwater18.07Chemie (HOH)
Sequence modifications
A: 1 - 142 (UniProt: O15392)
PDBExternal DatabaseDetails
Gly -3-expression tag
Ser -2-expression tag
His -1-expression tag
Glu 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight18241.6
Non-Polymers*Number of molecules1
Total formula weight65.4
All*Total formula weight18307.0
*Water molecules are not included.

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PDB entries from 2024-11-13

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