7LAU
Crystal structure of the first bromodomain (BD1) of human BRD2 bound to ERK5-IN-1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Bromodomain-containing protein 2 | polymer | 122 | 14471.9 | 1 | UniProt (U3KQA6) Pfam (PF00439) In PDB | Homo sapiens (Human) | |
| 2 | A | 11-cyclopentyl-2-({2-ethoxy-4-[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]phenyl}amino)-5-methyl-5,11-dihydro-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one | non-polymer | 638.8 | 1 | Chemie (VYJ) | |||
| 3 | water | water | 18.0 | 27 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 14471.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 638.8 | |
| All* | Total formula weight | 15110.7 |
