7LAJ
Crystal structure of the first bromodomain (BD1) of human BRD2 bound to Ro3280
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Bromodomain-containing protein 2 | polymer | 122 | 14471.9 | 1 | UniProt (U3KQA6) Pfam (PF00439) | Homo sapiens (Human) | |
| 2 | B (A) | 4-[(9-cyclopentyl-7,7-difluoro-5-methyl-6-oxo-6,7,8,9-tetrahydro-5H-pyrimido[4,5-b][1,4]diazepin-2-yl)amino]-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide | non-polymer | 543.6 | 1 | Chemie (79C) | |||
| 3 | C (A) | water | water | 18.0 | 105 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 14471.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 543.6 | |
| All* | Total formula weight | 15015.5 |
