7L9U

Crystal Structure of S-adenosylmethionine-dependent methyltransferase UmaA from Mycobacterium tuberculosis in complex with a 12-mer PEG

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	S-adenosylmethionine-dependent methyltransferase UmaA	polymer	294	34162.7	1	UniProt (Q6MX39) Pfam (PF02353) In PDB	Mycobacterium tuberculosis	SAM-dependent methyltransferase UmaA
2	A	DODECAETHYLENE GLYCOL	non-polymer		546.6	1	Chemie (12P)
3	A	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
4	A	NITRATE ION	non-polymer		62.0	2	Chemie (NO3)
5	A	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
6		water	water		18.0	311	Chemie (HOH)

Sequence modifications

A: 1 - 286 (UniProt: Q6MX39)

PDB	External Database	Details
Met -7	-	initiating methionine
Ala -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	34162.7
Non-Polymers*	Number of molecules	5
	Total formula weight	768.2
All*	Total formula weight	34930.9

*Water molecules are not included.