7L9P
Structure of human SHLD2-SHLD3-REV7-TRIP13(E253Q) complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | Pachytene checkpoint protein 2 homolog | polymer | 432 | 48562.5 | 6 | UniProt (Q15645) Pfam (PF00004) In PDB | Homo sapiens (Human) | Human papillomavirus type 16 E1 protein-binding protein,HPV16 E1 protein-binding protein,Thyroid hormone receptor interactor 13,Thyroid receptor-interacting protein 13,TRIP-13 |
2 | G, I, J, K | Mitotic spindle assembly checkpoint protein MAD2B | polymer | 211 | 24323.3 | 4 | UniProt (Q9UI95) Pfam (PF02301) In PDB | Homo sapiens (Human) | Mitotic arrest deficient 2-like protein 2,MAD2-like protein 2,REV7 homolog,hREV7 |
3 | Y, X | Shieldin complex subunit 2, Shieldin complex subunit 3 chimera | polymer | 99 | 10678.1 | 2 | UniProt (Q86V20) UniProt (Q6ZNX1) In PDB | Homo sapiens (Human) | Protein FAM35A,RINN1-REV7-interacting novel NHEJ regulator 2,Shield complex subunit 2,REV7-interacting novel NHEJ regulator 1,Shield complex subunit 3 |
4 | A, B, C, D, E | PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | non-polymer | 523.2 | 5 | Chemie (AGS) |
Sequence modifications
A, B, C, D, E, F: 2 - 432 (UniProt: Q15645)
G, I, J, K: 2 - 211 (UniProt: Q9UI95)
Y, X: 2 - 16 (UniProt: Q86V20)
Y, X: 33 - 89 (UniProt: Q6ZNX1)
PDB | External Database | Details |
---|---|---|
Ser 1 | - | expression tag |
Gln 253 | Glu 253 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Ser 1 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Met 1 | - | initiating methionine |
Gly 17 | - | linker |
Ser 18 | - | linker |
Gly 19 | - | linker |
Ser 20 | - | linker |
Gly 21 | - | linker |
Ser 22 | - | linker |
Gly 23 | - | linker |
Ser 24 | - | linker |
Gly 25 | - | linker |
Ser 26 | - | linker |
Gly 27 | - | linker |
Ser 28 | - | linker |
Gly 29 | - | linker |
Ser 30 | - | linker |
Gly 31 | - | linker |
Ser 32 | - | linker |
PDB | External Database | Details |
---|---|---|
Ala 90 | - | expression tag |
Ser 91 | - | expression tag |
Arg 92 | - | expression tag |
Glu 93 | - | expression tag |
Glu 94 | - | expression tag |
Ile 95 | - | expression tag |
Met 96 | - | expression tag |
Ala 97 | - | expression tag |
Thr 98 | - | expression tag |
Leu 99 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 12 |
Total formula weight | 410025.0 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 2616.2 | |
All* | Total formula weight | 412641.2 |